胺碘酮与普罗帕酮在阵发性室上性心动过速患者院前急救中的应用效果对比

Comparison of the Application Effect of Amiodarone and Propafenone in Prehospital Emergency Treatment of Patients with Paroxysmal Supraventricular Tachycardia

目的:对比胺碘酮与普罗帕酮在阵发性室上性心动过速(PSVT)患者院前急救中的应用效果。方法:回顾性收集郑州大学人民医院2019年4月—2020年9月接受院前急救的102例PSVT患者资料,根据不同治疗药物分为对照组50例与观察组52例,对照组使用胺碘酮,观察组使用普罗帕酮,对比两组患者治疗效果。结果:急救前,两组患者心率(HR)、舒张压(DBP)、收缩压(SBP)、呼吸频率(Rr)指标对比,差异无统计学意义(P>0.05);急救后,观察组总恢复效率明显高于对照组,差异有统计学意义(χ^(2)=4.258,P<0.05);两组患者HR、DBP、SBP指标明显下降而Rr指标明显上升,且观察组HR指标明显低于对照组而Rr指标明显高于对照组,差异有统计学意义(t=8.143、0.931、1.134、2.989,P<0.05);观察组心率恢复时长、住院时长明显低于对照组,差异有统计学意义(t=3.500、3.646,P<0.05);两组患者副反应总发生率对比,差异无统计学意义(χ^(2)=0.628,P>0.05)。结论:在PSVT患者院前急救过程中使用普罗帕酮进行治疗,可有效提高患者恢复效率,改善患者各项生理指标,临床应用价值更高。

Objective:To compare the effect of amiodarone and propafenone in the prehospital emergency treatment of patients with paroxysmal supraventricular tachycardia(PSVT).Methods:The data of 102 patients with PSVT who received pre-hospital first aid in the hospital from April 2019 to September 2020 were retrospectively collected,and they were divided into control group(50 cases)and observation group(52 cases)according to different treatment drugs.The control group was given amiodarone,and the observation group was given propafenone.The treatment effects of the two groups of patients were compared.Results:Before emergency treatment,there was no significant difference in heart rate(HR),diastolic blood pressure(DBP),systolic blood pressure(SBP),and respiratory rate(Rr)between the two groups(P>0.05).After first aid,the total recovery efficiency of the observation group was significantly higher than that of the control group,and the difference was statistically significant(χ^(2)=4.258,P<0.05).The indexes of HR,DBP and SBP in the two groups decreased significantly while the index of Rr increased significantly,and the index of HR in the observation group was significantly lower than that of the control group while the index of Rr was significantly higher than that of the control group,the difference was statistically significant(t=8.143,0.931,1.134,2.989,P<0.05).The heart rate recovery time and hospitalization time in the observation group were significantly lower than those in the control group,and the differences were statistically significant(t=3.500,3.646,P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(χ^(2)=0.628,P>0.05).Conclusion:The use of propafenone in the pre-hospital emergency treatment of PSVT patients can effectively improve the recovery efficiency of patients,improve various physiological indicators of patients,and has higher clinical application value.