经皮椎体成形术治疗骨质疏松性胸腰椎压缩骨折临床疗效分析

Clinical Analysis of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Thoracolumbar Compression Fractures

目的分析经皮椎体成形术(PVP)治疗骨质疏松(OSP)性胸腰椎压缩骨折临床效果。方法随机选取南宁市第七人民医院2018年7月—2021年1月收治的60例OSP性胸腰椎压缩骨折患者作为研究对象,按随机数字表法将其分为R组与T组,各30例。R组予以PVP治疗,T组予以保守治疗,分析两组治疗价值。结果治疗后5 dR组与T组疼痛程度评分分别为(1.34±0.25)分、(3.47±0.57)分,两组比较差异有统计学意义(t=18.744,P<0.001);治疗后R组与T组椎体高度丢失率分别为(10.25±2.36)、(18.25±3.65)g/cm^(2),两组比较差异有统计学意义(t=10.081,P<0.001);治疗后R组与T组Cobb角分别为(10.25±7.25)°、(17.65±3.34)°,两组比较差异有统计学意义(t=5.078,P<0.001);经治疗后R组与T组神经状况评分分别为(91.23±10.36)分、(80.34±9.34)分,两组比较差异有统计学意义(t=4.276,P<0.001);经治疗后R组与T组肢体功能评分分别为(93.56±10.26)分、(65.34±8.73)分,两组比较差异有统计学意义(t=11.474,P<0.001);经治疗后R组与T组社会功能评分分别为(94.56±10.26)分、(65.72±8.64)分,两组比较差异有统计学意义(t=11.777,P<0.001)。结论OSP性胸腰椎压缩骨折实施PVP治疗可获得显著效果,值得推广。

Objective To analyze the clinical effect of percutaneous vertebroplasty(PVP)in the treatment of osteoporotic(OSP)thoracolumbar compression fractures.Methods 60 patients with OSP thoracolumbar compression fractures treated in Nanning Seventh People's Hospital from July 2018 to January 2021 were randomly selected as the research objects.They were randomly divided into group R and group T,with 30 cases in each group.Group R was treated with PVP and group T was treated with conservative treatment.The therapeutic value of the two groups was analyzed.Results 5 d after treatment,the pain degree scores of group R and group T were(1.34±0.25)points and(3.47±0.57)points,respectively,the difference between the two groups was statistically significant(t=18.744,P<0.001).After treatment,the loss rates of vertebral body height in group R and group T were(10.25±2.36)g/cm^(2) and(18.25±3.65)g/cm^(2),respectively,the difference between the two groups was statistically significant(t=10.081,P<0.001).After treatment,the Cobb angles of group R and group T were(10.25±7.25)°and(17.65±3.34)°,respectively,the difference between the two groups was statistically significant(t=5.078,P<0.001).After treatment,the scores of neurological status in group R and group T were(91.23±10.36)points and(80.34±9.34)points,respectively,the difference between the two groups was statistically significant(t=4.276,P<0.001).After treatment,the limb function scores of group R and group T were(93.56±10.26)point and(65.34±8.73)points,respectively,the difference between the two groups was statistically significant(t=11.474,P<0.001).After treatment,the scores of social function in group R and group T were(94.56±10.26)points and(65.72±8.64)points,respectively,the difference between the two groups was statistically significant(t=11.777,P<0.001).Conclusion PVP treatment of OSP thoracolumbar compression fractures can obtain significant effect and is worthy of promotion.