鼻腔冲洗对经鼻蝶入路垂体瘤切除术后患者鼻腔嗅觉及舒适度的影响研究

The Effect of Nasal Irrigation on Nasal Olfactory and Comfort of Patients after Pituitary Tumor Resection via Nasal Sphenoid Approach

目的研究鼻腔冲洗对经鼻蝶入路垂体瘤切除术后患者鼻腔嗅觉及舒适度的影响。方法方便选取2020年1月—2021年6月在该院接受治疗的104例经鼻蝶入路垂体瘤切除术后患者进行研究,经随机数字表法分组。对照组(n=52)行常规护理,观察组(n=52)在对照组的基础上采用0.9%氯化钠溶液行鼻腔冲洗。对比两组嗅觉功能、鼻阻塞症状、生活质量及舒适度。结果术后1个月,观察组患者的嗅觉功能评分为(1.85±0.11)分,对照组为(2.15±0.25)分,观察组明显低于对照组,差异有统计学意义(t=7.921,P<0.05)。术后1周、1个月,观察组患者的NOSE评分分别为(38.25±3.12)分、(29.36±3.27)分,对照组分别为(42.36±3.24)分、(36.35±3.24)分,观察组明显低于对照组,差异有统计学意义(t=6.589、10.950,P<0.05)。术后1周、1个月,观察组患者的生理问题评分分别为(36.24±3.12)分、(28.35±3.21)分,对照组分别为(40.25±3.21)分、(35.24±3.21)分;观察组睡眠功能症状评分分别为(9.65±1.18)分、(5.54±1.12)分,对照组分别为(12.35±1.27)分、(8.25±1.24)分;观察组心理情感结果分别为(16.35±2.74)分、(10.24±2.18)分,对照组分别为(20.38±2.45)分、(15.31±2.11)分,观察组均低于对照组,差异有统计学意义(t=6.450、10.945、11.231、11.695、7.906、12.051,P<0.05)。术后1周、1个月,观察组患者的VAS评分分别为(3.26±1.12)分、(1.85±0.35)分,对照组分别为(4.25±1.21)分、(2.84±0.45)分,观察组明显低于对照组,差异有统计学意义(t=4.330、12.523,P<0.05)。结论采用0.9%氯化钠溶液对经鼻蝶入路垂体瘤切除术后的患者进行鼻腔冲洗,不仅能改善患者的鼻阻塞症状,还能在一定程度上促进患者嗅觉功能的恢复,有助于进一步提高患者的生活质量及舒适度。

Objective To study the effect of nasal irrigation on nasal olfactory and comfort of patients after pituitary tumor resection via nasal sphenoid approach.Methods Conveniently selected 104 patients who were treated in the hospital from January 2020 to June 2021 after pituitary tumor resection through the nasal sphenoid approach for the study,and were grouped by random number table method.The control group(n=52)underwent routine care,and the observation group(n=52)used 0.9%sodium chloride solution on the basis of the control group for nasal irrigation.The olfactory function,nasal obstruction symptoms,quality of life and comfort were compared between the two groups.Results One month after the operation,the olfactory function score of the observation group was(1.85±0.11)points,and the control group was(2.15±0.25)points.The observation group was significantly lower than the control group,and the difference was statistically significant(t=7.921,P<0.05).One week and one month after the operation,the NOSE scores of the observation group were(38.25±3.12)points and(29.36±3.27)points,and the control group were(42.36±3.24)points and(36.35±3.24)points,respectively.The observation group was significantly lower than the control group,and the difference was statistically significant(t=6.589,10.950,P<0.05).One week and one month after operation,the observation group's physiological problem scores were(36.24±3.12)points and(28.35±3.21)points,and the control group were(40.25±3.21)points and(35.24±3.21)points,respectively.The sleep function symptom scores of the observation group were(9.65±1.18)points and(5.54±1.12)points,and the control group were(12.35±1.27)points and(8.25±1.24)points,respectively.The psychological and emotional results of the observation group were(16.35±2.74)points and(10.24±2.18)points,and the control group were(20.38±2.45)points and(15.31±2.11)points.The observation group was lower than the control group,the difference was statistically significant(t=6.450,10.945,11.231,11.695,7.906,12.051,P<0.05).One week and one month after the operation,the VAS scores of the observation group were(3.26±1.12)points and(1.85±0.35)points,and the control group were(4.25±1.21)points and(2.84±0.45)points,respectively.The observation was significantly lower than the control group,the difference was statistically significant(t=4.330,12.523,P<0.05).Conclusion The 0.9%sodium chloride solution was used to flush the nasal cavity of patients after pituitary tumor resection through the transnasal approach.it can not only improve the symptoms of nasal obstruction in patients,but.also promote the recovery of the patient's olfactory function to a certain extent,which helps to further improve the quality of life and comfort of patients.