南疆维吾尔族儿童泌尿结石病的研究

Study on Urinary Calculi in Uygur Children in Southern Xinjiang

目的分析南疆维吾尔族儿童泌尿结石病临床特点及影响因素。方法于2020年1月—2021年2月选取南疆喀什地区莎车县维吾尔族泌尿结石病患儿292例(年龄≤6岁)作为观察组,分析一般资料与疾病情况;选取同期入院体检的正常儿童292名作为对照组。以随机抽样调查,收集患者一般资料与疾病情况,既往家族史、喂养方式、生活习惯、饮食水源特点等,单因素分析患病率,初步筛选与儿童泌尿系统结石病发病关系密切的研究因素,纳入多因素条件Logistic回归进行疾病多危险因素分析。结果292例患儿中,男性(75.68%)多于女性(24.32%),结石部位主要为肾结石(38.01%),结石成分类型主要为混合型(62.67%)。292例患儿中,经单因素分析,既往家族史、喂养方式、生活习惯、饮食水源特点、日饮水量均为影响儿童泌尿结石病的因素(P<0.05)。将是否形成泌尿结石病作为因变量,表2中P<0.05的变量作为自变量;经多因素条件Logistic回归分析,结果显示:既往家族史、喂养方式、生活习惯、饮食水源特点、日饮水量为儿童泌尿系结石形成的独立危险因素(P<0.05)。结论既往家族史、不良喂养方式、饮食习惯、生活习惯、日饮水量等因素,均会增加泌尿系结石疾病的发生风险,及时纠正不良习惯,有助于降低儿童泌尿系结石发生率,提高患儿生活质量。

Objective To analyze the clinical characteristics and influencing factors of urinary calculi in Uygur children in southern Xinjiang.Methods From January 2020 to February 2021,292 Uyghur children with urinary stone disease(age≤6 years)in Shache County,Kashgar,South Xinjiang were selected as the observation group to analyze general information and disease conditions.A total of 292 normal children admitted to the hospital for physical examination during the same period were selected as the control group.Random sample surveys were used to collect patients'general information and disease conditions,past family history,feeding methods,living habits,characteristics of diet and water sources,etc.Univariate analysis of prevalence,preliminary screening of research factors that were closely related to the incidence of urinary calculi in children,including multivariate conditional Logistic regression for disease multi-risk factor analysis.Results Among the 292 children,males(75.68%)were more than females(24.32%).The main stones were kidney stones(38.01%),and the main types of stones were mixed(62.67%).Among the 292 children,through univariate analysis,past family history,feeding methods,living habits,characteristics of diet and water source,and daily water consumption were all factors affecting children's urinary calculi disease(P<0.05).The formation of urinary calculus disease was taken as the dependent variable,and the variables with P<0.05 in Table 2 were used as independent variables.After multi-factor conditional logistic regression analysis,the results showed that past family history,feeding methods,living habits,characteristics of diet and water source,and daily water consumption were independent risk factors for the formation of urinary calculi in children(P<0.05).Conclusion Factors such as past family history,poor feeding methods,eating habits,living habits,and daily water intake all increase the risk of urinary calculi diseases.Correcting bad habits in time can help reduce the incidence of urinary stones in children and improve the quality of life of children.