抑郁症患者应用脑电生物反馈与松弛治疗的对照研究

Controlled Study on the Patients of Electroencephalography(EEG)Biofeedback and Versus Relaxation Therapy in Patients With Depression

目的探讨脑电生物反馈治疗与松弛治疗对抑郁症患者的疗效。方法选取2019年7月—2020年11月本院住院治疗的70例抑郁症患者,随机分配到研究组(行脑电生物反馈治疗)与对照组(行松弛治疗),且两组在治疗期间均服用等量草酸艾司西酞普兰,分别在治疗前和治疗至第2、4、6周的周末采用症状自评量表(SCL-90)和汉密尔顿抑郁量表(HAMD)评定其疗效。结果研究组痊愈率高于对照组,差异有统计学意义(P<0.05);治疗至第2、4周末,研究组SCL-90中的躯体化、抑郁、焦虑因子评分低于对照组(P<0.05),治疗至6周后,研究组SCL-90中的强迫、抑郁、焦虑、恐怖因子评分低于对照组(P<0.01);研究组治疗至4、6周末,HAMD评分显著低于对照组(P<0.01)。结论脑电生物反馈治疗与松弛治疗均能改善抑郁患者的抑郁症状,且脑电生物反馈治疗疗效优于松弛治疗。

Objective To examine the effects of EEG biofeedback therapy and relaxation therapy on patients with depression.Methods A total of 70 patients with depression hospitalized in our hospital from July 2019 to November 2020 were randomly assigned to the study group(EEG biofeedback treatment)and the control group(relaxation treatment),both groups took the same amount of escitalopram oxalate during the treatment.The curative effects were evaluated by symptom checklist 90(SCL-90)and Hamilton depression scale(HAMD)before treatment and at the weekend of the second,fourth and sixth weeks.Results The cure rate in the study group was significantly higher than that in the control group(P<0.05);the scores of somatization,depression and anxiety factors in the study group were lower than those in the control group at the end of the second and fourth weeks of treatment(P<0.05),the scores of compulsion,depression,anxiety and phobia in SCL-90 in the study group were lower than those in the control group at the end of the sixth weeks of treatment(P<0.01);the HAMD scores in the study group were significantly lower than those in the control group at the end of the fourth and sixth weeks of treatment(P<0.01).Conclusion Biofeedback and relaxation therapy bothimprove depressive symptoms in depressed patients.Biofeedback therapy showed better results than relaxation therapy.