急性缺血性脑卒中急诊头颈联合CT血管造影对肾功能的影响研究

Effect of Emergency Head and Neck Combined With CTA on Renal Function in Acute Cerebral Apoplexy

目的探讨研究急性脑卒中急诊头颈联合CT血管造影(CT angiography,CTA)对肾功能的影响。方法选取我院在2019年2月—2020年3月确诊并治疗的162例急性脑卒中患者,所有患者均接受急诊头颈联合CTA检查。观察所有患者实施CTA检查后发生对比剂肾病(contrast-induced nephropathy,CIN)的情况。比较不同合并症患者实施CTA检查前后的相关肾功能指标[肌酐(creatin,Cr)水平、胱抑素C(cystatin C,Cys C)水平及肾小球滤过率(glomerular filtration,GFR)]水平变化情况。结果所有患者实施CTA检查后并未发生CIN。所有患者实施CTA检查前、后的相关肾功能指标:Cr水平、Cys C水平及GFR水平变化差异均无统计学意义(P均>0.05)。高血压并糖尿病者实施CTA检查前后的相关肾功能指标比较,Cr水平、Cys C水平及GFR水平变化差异均无统计学意义(P均>0.05)。单纯高血压患者实施CTA检查前后的相关肾功能指标比较,Cr水平、Cys C水平及GFR水平变化差异均无统计学意义(P均>0.05)。单纯糖尿病患者实施CTA检查前后的相关肾功能指标比较,Cr水平、Cys C水平及GFR水平变化差异均无统计学意义(P均>0.05)。结论给予急性脑卒中患者使用碘海醇对比剂进行急诊头颈联合CTA检查,CTA检查前后患者的相关肾功能指标未发生显著性改变,不会对肾功能产生影响。

Objective To investigate the effect of head and neck combined with CTA on renal function in acute stroke emergency.Methods A total of 162 acute stroke patients diagnosed and treated in our hospital from February 2019 to March 2020 were selected.All patients underwent emergency head and neck combined CTA examination.The occurrence of contrast-induced nephropathy(CIN)in all patients after CTA examination were observed.Related renal function indicators before and after CTA examination in patients with different comorbidities:creatin(Cr)level,cystatin C(Cys C)level,and glomerular filtration rate(GFR)level changes happening.Results No CIN occurred in all patients after CTA examination.There was no significant difference in the changes of all patients before and after CTA examination:Cr level,Cys C level and GFR level(all P>0.05).The related renal function indexes before and after CTA examination in patients with hypertension and diabetes:Cr level,Cys C level and GFR level changes were not significantly different(P>0.05).There was no significant difference in the changes in the related renal function indexes of patients with simple hypertension before and after CTA examination:Cr level,Cys C level and GFR level(P>0.05).The related renal function indexes before and after CTA examination in patients with simple diabetes:Cr level,Cys C level and GFR level were not significantly different(all P>0.05).Conclusion Iohexol contrast agent is given to patients with acute stroke for emergency head and neck combined CTA examination.There is no significant change in the relevant renal function indexes of the patients before and after the CTA examination,and it will not affect the renal function.