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白细胞介素1β在头颈鳞状细胞癌中的作用

Role of interleukin-1 p in malignant tumors
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摘要 头颈鳞状细胞癌(head and neck squamous cell carcinoma,HNSCC)是一类影响人类健康的重要疾病,患者生存时问普遍较短,生活质量较差,给家庭和社会带来沉重负担.目前为止,HNSCC的病因尚未明确,近年来越来越多的研究聚焦于人体免疫调节机制及炎症反应与HNSCC的关系.其中,白细胞介素-1β(IL-1β)作为一个重要的细胞因子,在恶性肿瘤尤其是HNSCC的发生与发展中起着十分重要的作用.本文就IL-1β在HNSCC及肿瘤微环境中的作用以及相关机制做一综述,为探讨肿瘤病因及治疗提供新思路.
作者 王蓉 尹高菲 郭伟 刘宏飞 黄俊伟 黄志刚 Wang Rong;Yin Gaofei;Guo Wei;Liu Hongfei;Huang Junwei;Huang Zhigang(Department of Otorhinolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
机构地区 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2022年第1期19-22,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 国家自然科学基金(82071032、82072997)。
关键词 白细胞介素1Β 头颈部肿瘤 肿瘤微环境
分类号 R739.91 [医药卫生—肿瘤]
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国际耳鼻咽喉头颈外科杂志
2022年 第1期

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