食管胃结合部腺癌根治性切除术后并发症的相关因素

Related factors of postoperative complications of radical resection for adenocarcinoma ofesophagogastric junction

食管胃结合部腺癌(AEG)因其特殊的解剖部位,其术后的并发症发生率明显高于其他部位的胃癌。胃癌根治术后并发症的发生会显著降低患者术后生活质量和术后生存率。AEG术后并发症的发生受到患者因素(高龄、肥胖、术前营养状况)、手术因素(手术路径、手术方式、切除范围、预防性联合脏器切除等)、肿瘤因素(分期等)等多方面的影响。而优化围手术期的管理,制定合适规范的手术方式,是预防AEG术后并发症的关键所在。所以,在保证肿瘤根治的同时,力求减少术后并发症的发生,才能使AEG患者真正获益。

Adenocarcinoma of esophagogastric junction(AEG)is at a special anatomic site with obviously higher morbidity of postoperative complication than gastric cancers at other sites.Postoperative quality of life and survival rate are influenced by the occurrence of complications.Moreover,the perioperative complications are associated with multiple factors such as patient factors(advanced age,obesity and preoperative nutritional status),surgical factors(surgical route,surgical procedure,resection range and prophylactic multivisceral resection),tumor factors(size,stage)etc.Optimizing perioperative management and formulating standardized surgical methods are the key points to prevent postoperative complications of AEG.In conclusion,we should strive to ensure the radical resection and reduce the occurrence of postoperative complications in order to truly benefit patients.