胰腺癌术后患者生活质量及干预策略的研究进展

Research advances in quality of life and intervention strategies in patients with pancreatic cancer after surgery

胰腺癌是致死率极高的恶性肿瘤之一,5年生存率仅为9%,手术切除是患者长期生存的主要治疗手段,联合化疗的5年生存率可提高到50%。随着发病率、早期检出率逐年上升,接受手术切除术的患者逐渐增加。由于胰腺切除术的复杂性,国内仅局限于病死率、并发症、围术期治疗与护理的研究,忽略了患者生理功能、心理和社会功能、症状等与生活质量相关的感受。本文对胰腺癌术后生活质量现状以及干预策略相关的国内外研究成果进行综述,为临床实践以及未来研究方向提供了参考。

Pancreatic cancer is a major cause of cancer-associated mortality. The 5-year survival rate is only 9%. Surgical resection reminds the primary curative treatment for long-term survival in patients and the 5-year survival rate can be increased to 50% after surgery combined with chemotherapy. As the incidence and early detection rate increasing, the number of patients undergoing surgical resection is increasing. Due to the high complexity of pancreatectomy, domestic clinical and research only focus on mortality, complications, and perioperative treatment, ignoring the patient’s physiological function, psychosocial and social function, symptoms, and other feelings related to the quality of life. This article reviewed domestic and foreign research results related to current quality of life and intervention strategies for pancreatic cancer patients, so as to provide reference for clinical practice and future research.