抗菌肽在牙本质粘接剂中应用的研究进展

Research progress on the application of antimicrobial peptides in dentin adhesives

近几十年,牙本质粘接剂历经多代改良趋向多功能化和操作简便化,并在口腔修复治疗中广泛应用。为获得理想的远期修复效果,牙本质粘接剂在具备良好的物理化学和机械性能基础上,还需具备有效的抗龋性能。该文将重点从抗菌肽的抗菌作用机制、抗菌肽的种类、在牙本质粘接剂中的应用及防龋效果等方面展开综述,并对抗菌肽在牙本质粘接剂应用中面临的挑战和发展前景作出展望。

In recent decades,dentin adhesives have undergone many generations of improvements and tend to be multi-functional and easy to operate,and are widely used in oral prosthetic treatment.In order to obtain an ideal long-term restoration effect,in addition to good physical,chemical and mechanical properties of dentin adhesives,effective anti-caries properties are also key factors that need to be considered.This paper will focus on the antimicrobial mechanism of antimicrobial peptides,the types of antimicrobial peptides,their application in dentin adhesives and their anti-caries effect.Challenges and prospects for the application of antimicrobial peptides in dentin adhesives are also discussed.