髓质海绵肾的诊断研究进展

Review on the diagnosis of medullary sponge kidney

髓质海绵肾(MSK)是一种肾脏畸形,通常表现为肾钙质沉着症和复发性肾结石等,同时需要使用昂贵且耗时的静脉尿路造影(IVU)进行诊断。尽管IVU仍然是目前诊断MSK的金标准,但其他方法如多层螺旋CT(MDCT)、核磁共振成像(MRI)、乃至生物标志物正在迅速崛起,为MSK的早期检测和诊断提供了希望。本文对MSK最新的影像学检查、生物标志物的诊断方法进行综述。

Medullary sponge kidney(MSK)is a kidney malformation,usually characterized by nephrocalcinosis and recurrent kidney stones,and requires an expensive and time-consuming intra-venous urography(IVU)for diagnosis.Although IVU is still the gold standard for diagnosing MSK,other methods such as multi-detector computed tomography(MDCT),magnetic resonance imaging(MRI),and even biomarkers are rapidly emerging,providing hope for early detection and diagnosis of MSK.In this paper,the latest imaging examination of MSK and the study of diagnostic methods of biomarkers are reviewed.