23G+、25G+微创玻璃体切割术治疗增殖性糖尿病性视网膜病变的效果比较

Comparison of the effects of 23G+and 25G+minimally invasive vitrectomy in the treatment of proliferative diabetic retinopathy

目的比较23G+、25G+微创玻璃体切割术治疗增殖性糖尿病性视网膜病变的效果。方法选取2018年1月至2020年12月我院收治的152例增殖性糖尿病性视网膜病变患者作为研究对象,遵循随机数字表法将其分为参照组和研究组,各76例。参照组开展23G+微创玻璃体切割术,研究组开展25G+微创玻璃体切割术。比较两组的临床效果。结果术后7、14 d,研究组的视力高于参照组(P<0.05)。研究组的术后并发症总发生率低于参照组(P<0.05)。研究组的视力改善率高于参照组(P<0.05)。术后1个月,研究组的黄斑区视网膜厚度低于参照组,BCVA高于参照组(P<0.05)。术后3 d,研究组的P-VEP P50、N95波振幅高于参照组,P50、N95潜伏期短于参照组(P<0.05)。术后3个月,研究组的生理功能、精神健康、活力、社会功能、生理职能、情感职能、躯体疼痛、总体健康评分高于参照组(P<0.05)。结论相较于23G+微创玻璃体切割术,25G+微创玻璃体切割术治疗增殖性糖尿病性视网膜病变的效果更好,能有效改善患者视力、视网膜功能,降低并发症发生率,改善生活健康状态。

Objective To compare the effects of 23G+and 25G+minimally invasive vitrectomy in the treatment of proliferative diabetic retinopathy.Methods A total of 152 patients with proliferative diabetic retinopathy admitted in our hospital from January 2018 to December 2020 were selected as the research objects.The patients were divided into reference group and study group follow the random number table method,with 76 cases in each group.The reference group underwent 23G+minimally invasive vitrectomy and the study group underwent 25G+minimally invasive vitrectomy.The clinical effects of the two groups were compared.Results At 7 and 14 d after operation,the visual acuity of the study group was higher than that of the reference group(P<0.05).The total incidence of postoperative complications in the study group was lower than that in the reference group(P<0.05).The improvement rate of visual acuity in the study group was higher than that in the reference group(P<0.05).One month after operation,the macular retinal thickness in the study group was lower than that in the reference group,and BCVA was higher than that in the reference group(P<0.05).Three days after operation,the wave amplitude of P-VEP P50 and N95 in the study group were higher than those in the reference group,and the incubation of P50 and N95 were shorter than those in the reference group(P<0.05).Three months after operation,the scores of physiological function,mental health,vitality,social function,physiological function,emotional function,physical pain and overall health in the study group were higher than those in the reference group(P<0.05).Conclusion Compared with 23G+minimally invasive vitrectomy,25G+minimally invasive vitrectomy in the treatment of proliferative diabetic retinopathy has better effect.It can effectively ameliorate the visual acuity and retinal function,reduce the incidence of complications and improve the life health status.