柴胡香苏饮加减治疗慢性浅表性胃炎的临床有效率及价值分析

Analysis of Clinical Effectiveness and Value of Chaihu Xiangsu Decoction in the Treatment of Chronic Superficial Gastritis

目的:分析柴胡香苏饮加减治疗慢性浅表性胃炎的临床有效率及价值。方法:选取106例研究对象,均为2019年2月~2021年2月在某院门诊就诊的慢性浅表性胃炎患者,采用电脑盲选法进行分组,分为对照组(常规西药治疗)和研究组(柴胡香苏饮)各53例,连续治疗3个月后,对比分析两组的胃肠激素水平,统计炎症介质,观察不良反应。结果:在血清胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(PGⅡ)、胃泌素、胃动素、生长抑素、血清白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)以及不良反应发生率上,研究组优于对照组(P<0.05),差异存在统计学意义。结论:柴胡香苏饮加减用于慢性浅表性胃炎的效果显著,对于胃肠激素水平的改善具有促进作用,有利于减轻患者的炎症反应,减少不良反应的发生。

Objective:To analyze the clinical effectiveness and value of Chaihu Xiangsu decoction in the treatment of chronic superficial gastritis.Methods:A total of 106 patients with chronic superficial gastritis who were treated in a hospital from February 2019 to February 2021 were selected and divided into the control group(conventional western medicine treatment,n=53)and the research group(Chaihu Xiangsu decoction,n=53)by computer blind selection.After continuous treatment for 3 months,the gastrointestinal hormone levels of the two groups were compared and analyzed,the inflammatory mediators were counted,and the adverse reactions were observed.Results:The serum pepsinogenⅠ(PGⅠ),pepsinogenⅡ(PGⅡ),gastrin,motilin,somatostatin,serum interleukin-2(IL-2),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)and the incidence of adverse reactions in the study group were better than those in the control group(P<0.05).Conclusion:The Chaihu Xiangsu decoction has a significant effect on chronic superficial gastritis,which has a promoting effect on the improvement of gastrointestinal hormone levels,and is conducive to reducing the inflammatory reaction of patients and reducing the incidence of adverse reactions.