MSCT评价肝脏体积、脾脏体积在诊断肝硬化和肝脏储备功能中的应用

Application of MSCT in Evaluating Liver Volume and Spleen Volume in Diagnosing Liver Cirrhosis and Liver Reserve Function

本研究讨论多层螺旋CT(MSCT)评价肝脏体积、脾脏体积在诊断肝硬化及肝脏储备功能中的应用价值。采用病例对照的方式进行研究。选取确诊的120例肝硬化患者作为病例组,同期120例年龄、性别基本匹配且无肝脏疾患的志愿者作为对照组,采用MSCT检测两组研究对象的全肝、各肝叶和脾脏的体积,并进行比较。病例组患者的全肝体积、右半肝体积、左内叶体积、全肝/脾脏体积值均低于对照组且差异具有统计学意义(P<0.05);病例组患者的脾脏体积、左外叶体积高于对照组且差异具有统计学意义(P<0.05)。肝脏/脾脏体积值、肝脏体积诊断患者肝硬化的ROC曲线下面积(AUC)值分别为0.902、0.837。MSCT检查肝脏体积、脾脏体积对于判断患者肝硬化及肝脏储备功能具有较高的临床参考价值。

This study discussed the application value of MSCT in evaluating liver volume and spleen volume in the diagnosis of liver cirrhosis and liver reserve function.In this study,a case-control study was conducted.A total of 120 patients with liver cirrhosis(case group)and 120 volunteers with matched age,gender and no liver disease(control group)were selected.The volumes of the whole liver,liver lobe and spleen of the two groups were detected by MSCT.The total liver volume,right half liver volume,left internal lobe volume,and total liver/spleen volume ratio in the case group were lower than those in the control group,and the differences were statistically significant(P<0.05).The spleen volume and left lateral lobe volume in the case group were higher than those in the control group,and the difference was statistically significant(P<0.05).The AUC values under ROC curve of liver/spleen volume and liver volume were 0.902 and 0.837,respectively.MSCT examination of liver volume and spleen volume has high clinical reference value for judging liver cirrhosis and liver reserve function.