大肠息肉肠镜下表现及其癌变与TG、NLR的关系

Colonoscopic Manifestations of Colorectal Polyps and Its Carcinogenesis Relationship with TG and NLR

本研究探讨大肠息肉肠镜表现及病理,以及与甘油三酯(TG)、中性粒细胞与淋巴细胞比值(NLR)的相关性。选取422例大肠息肉患者为研究对象,分析患者肠镜下表现、病理分布特点,同时分析息肉癌变和非息肉癌变患者TG、NLR等指标差异。共检出息肉1084枚,息肉以无蒂息肉为主;病理显示腺瘤性息肉较多;息肉癌变组患者年龄明显高于非息肉癌变组患者(P<0.05);息肉癌变组总胆固醇(TC)、TG、血尿酸(SUA)和NLR明显高于非息肉癌变组(P<0.05),而血小板计数(PLT)明显低于非息肉癌变组(P<0.05);Logistic回归分析结果显示,年龄、TG、NLR是息肉癌变的影响因素(P<0.05)。大肠息肉主要为无蒂息肉,病理主要为腺瘤性息肉;息肉癌变受患者年龄、TG、NLR水平的影响。

This study investigated the colonoscopy and pathology of colorectal polyps, and its correlation with triglyceride(TG), neutrophil lymphocyte ratio(NLR). 422 patients with colorectal polyps were selected as the subjects, the colonoscopic manifestations and pathological distribution characteristics of the patients were analyzed, and the differences of TG, NLR and other indicators between patients with polyp canceration and non polyp canceration were analyzed. A total of 1084 polyps were detected, most of which were sessile polyps. Pathology showed more adenomatous polyps. The age of polyp canceration group was significantly higher than that of non polyp canceration group(P<0.05). The total cholesterol(TC), triglyceride(TG), serum uric acid(SUA) and NLR were significantly higher than that in non polyp canceration group(P<0.05), while platelet count(PLT) was significantly lower than that in non polyp canceration group(P< 0.05). Logistic regression analysis showed that age, TG and NLR were the influencing factors of polyp carcinogenesis(P<0.05). Colorectal polyps are mainly sessile polyps, and adenomatous polyps are the main pathological types. The canceration of polyps are affected by age, TG and NLR levels.