腹腔镜联合超声引导经皮微波消融治疗子宫肌瘤疗效的研究

Study on the Efficacy of Laparoscopy Combined with Ultrasound-guidedPercutaneous Microwave Ablation in the Treatment of Hysteromyoma

本研究目的是探讨腹腔镜联合超声引导经皮微波消融治疗子宫肌瘤的疗效及安全性。选取140例子宫肌瘤患者为研究对象,共有肌瘤244枚,患者均给予腹腔镜联合超声引导经皮微波消融治疗。244枚子宫肌瘤中,完全消融151枚,占61.89%;术后1个月、术后3个月肌瘤体积较术前降低(P<0.05);术前,244个子宫肌瘤的回声特征主要为低回声,术后主要为均质等回声或高回声(P<0.05);术后1个月、术后3个月症状严重程度(SSS)评分较术前降低(P<0.05),健康相关生活质量(HRQL)评分较术前升高(P<0.05);不良反应中主要为消融区轻度疼痛、阴道排液和发热。腹腔镜联合超声引导经皮微波消融治疗子宫肌瘤有较好的疗效及安全性,值得临床使用。

This study investigated the efficacy and safety of laparoscopy combined with ultrasound-guided percutaneous microwave ablation in the treatment of uterine leiomyoma.A total of 140 patients with uterine fibroids were selected as research objects,including 244 fibroids.All patients were given laparoscopic combined ultrasound-guided percutaneous microwave ablation treatment.Among 244 uterine fibroids,151 were completely ablated,accounting for 61.89%.The volume of leiomyoma at 1 month and 3 months after operation was significantly lower than that before operation(P<0.05).Before surgery,the echo characteristics of 244 uterine fibroids were mainly hypoechoic,and the echo of uterine fibroids 3 months after surgery was mainly homogeneous iso-echo or hyperechoic(P<0.05).The symptom severity(SSS)score at 1 month and 3 months after operation was lower than that before operation(P<0.05),and the score of health-related quality of life(HRQL)was higher than that before operation(P<0.05).Adverse reactions were mainly mild pain in ablation zone,vaginal discharge and fever.Endoscopic combined with ultrasound-guided percutaneous microwave ablation has good efficacy and safety in the treatment of uterine fibroids and is worthy of clinical use.