高频超声对乳腺微小结节良恶性鉴别诊断意义

Significance of High Frequency Ultrasound in Differential Diagnosis of Benign and Malignant Breast Micronodules

本研究探讨高频超声对乳腺微小结节良恶性鉴别诊断意义及价值。回顾分析122例乳腺微小结节患者一般资料,患者均接受高频超声诊断,分析良恶性结节血流状况、血流参数、二维声像图特征,分析高频超声诊断价值。结果显示,与良性结节比较,恶性结节Ⅰ级占比更低,Ⅲ级占比更高(P<0.05);与良性结节比较,恶性结节血流阻力指数更高(P<0.05);高频超声诊断乳腺恶性微小结节阴性预测值、灵敏度、阳性预测值、特异度、准确度分别为95.0%、85.0%、89.5%、96.6%、93.7%,与病理诊断比较,差异无统计学意义(P>0.05)。表明高频超声可通过血流状态与参数对良恶性乳腺微小结节准确诊断,具有较高准确度与特异度,采用“BI-RADS”分级后,高频超声对乳腺病变的诊断准确性有了明显提高。

The purpose of this study was to explore the significance and value of high frequency ultrasound in the differential diagnosis of benign and malignant breast nodules. The general data of 122 patients with breast micronodules treated were analyzed retrospectively. All the patients were diagnosed by high frequency ultrasound. The blood flow status, blood flow parameters and two-dimensional sonographic features of benign and malignant nodules were analyzed. The diagnostic value of high frequency ultrasound was analyzed. The results showed that the proportion of grade Ⅰand grade Ⅲ of malignant nodules was lower than that of benign nodules(P<0.05), and the blood flow resistance index of malignant nodules was higher than that of benign nodules(P<0.05). The negative predictive value, sensitivity, positive predictive value, specificity and accuracy of high-frequency ultrasound in the diagnosis of malignant tiny breast nodules were 95.0%, 85.0%, 89.5%, 96.6% and 93.7%, respectively. There was no significant difference compared with pathological diagnosis(P>0.05). This study shows that high-frequency ultrasound can accurately diagnose benign and malignant breast small nodules by blood flow state and parameters, and has high accuracy and specificity. After using “BI-RADS” classification, the accuracy of high frequency ultrasound in the diagnosis of breast lesions has been significantly improved.