摘要
隐孢子虫是一种新现的单细胞人兽共患病原体。通过侵犯人和动物的小肠上皮细胞,导致宿主产生以腹泻为主的多种临床症状,可通过水源性、食物源性以及宿主间相互传播,具有重要的公共卫生学意义。研究显示,非人灵长类动物可感染多种隐孢子虫基因型,且该物种与人类基因相似度高,故需引起高度重视。本文就隐孢子虫在非人灵长类动物中的感染率、基因型、人兽共患风险进行综述。
Cryptosporidium is an emerging single-cell zoonotic pathogen.By invading human and animal small intestinal epithelial cells,the host produces a variety of clinical symptoms,mainly diarrhea.Spores of Cryptosporidium can be transmitted through water-borne,food-borne,and mutual transmission between hosts,which has important public health significance.Studies have shown that non-human primates can be infected with multiple Cryptosporidium genotypes.Moreover,this species has a high genetic similarity with humans,so it needs to be taken seriously.This article reviews the infection rates,genotypes,and zoonotic risk of Cryptosporidium in non-human primates.
作者
马天明
强钰
任广旭
吕刚
MA Tian‐ming;QIANG Yu;REN Guang‐xu;LV Gang(Key Laboratory of Translational Medicine for Tropical Diseases,NHC Key Laboratory of Control of Tropical Diseases,Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases,Department of Pathogenic Biology,Hainan Medical University,Haikou 571199,China)
出处
《海南医学院学报》
CAS
2022年第5期390-393,400,共5页
Journal of Hainan Medical University
基金
国家自然科学基金项目(82060375)
海南省自然科学基金创新研究团队项目(2018CXTD340)
国家自然科学基金项目(81760378)。