蜂毒肽抗炎作用及机制的研究进展

Research progress on the anti-inflammatory effect and mechanism of melittin

炎症是一种普遍现象,由先天性和获得性免疫系统触发,以维持体内稳态。这种现象通常会起到限制感染和修复损伤的作用,但是如果没有适当地分阶段进行,炎症可能会导致免疫功能异常。蜂毒是蜜蜂用来防护的毒素,数百年来,它已在东方用作抗炎药,用于治疗慢性炎性疾病。目前,越来越多的学者致力于蜂毒的主要成分蜂毒肽抗炎作用的研究,为其临床应用提供了一定的理论依据,为炎症性疾病的治疗提供了新的选择。

Inflammation is a pervasive phenomenon triggered by the innate and adaptive immunesystems to maintain homeostasis.The phenomenon normally leads to recovery from infection andhealing,but when not properly phased,inflammation may cause immune disorders.Bee venomis a toxin that bees use for their protection from enemies.It has been usedin the Orient as an anti-inflammatory medicine for the treatment of chronic inflammatory diseases for centuries.At present,a growing number of researchers work to the anti-inflammatory effect of melittin,the main component of bee venom,which provides theoretical basis for its clinical applicationand a new option for the treatment of inflammatory diseases.