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人乳头瘤病毒E6/E7 mRNA在宫颈病变中的研究进展 被引量:1

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摘要 近年来,宫颈癌在人群中的发病率显著升高,病死率也逐渐攀升,其好发人群正有从中老年女性转变为年轻女性的趋势。女性发生宫颈癌前病变乃至进展为宫颈癌,与高危型人乳头瘤病毒(HPV)在机体中的持续作用密不可分。其中,HPV E6/E7 mRNA在整个病变过程中起着重要作用,是用于预测宫颈病变恶性转归和监测宫颈癌复发的重要指标。通过对已有性生活女性定期进行宫颈癌筛查,可以及早发现癌前病变。本文就HPV E6/E7 mRNA定量检测及其他常用的检测方法在预测宫颈病变转归或宫颈癌复发方面的进展进行综述。
出处 《癌症进展》 2022年第2期113-115,177,共4页 Oncology Progress
基金 2019年合肥市卫生健康应用医学研究项目[合卫教科(2019)172号]。
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