2017年河南省肺癌流行现状及2010—2017年趋势分析

Incidence and Mortality of Lung Cancer in Henan Province in 2017 and Trend from 2010 to 2017

[目的]分析2017年河南省肺癌发病、死亡特征及2010—2017年发病、死亡变化趋势。[方法]利用河南省肿瘤登记处上报的、质控合格的肺癌发病与死亡资料,结合全省户籍人口数据,估算2017年分城乡、性别、年龄组别的肺癌发病率、死亡率、构成比、中标率、世标率和累积率(0~74岁),分析2010—2017年河南省肺癌中标发病(死亡)率的年度变化百分比(APC)及其95%置信区间(CI)。[结果]2017年河南省肺癌新发病例数为58749例,占全部恶性肿瘤新发病例数的20.27%,发病率为54.27/10万,中标率为39.20/10万,世标率为39.30/10万,累积率(0~74岁)为4.75%。肺癌死亡病例数为45921例,占全部恶性肿瘤死亡病例数的24.92%,死亡率为42.42/10万,中标率为29.58/10万,世标率为29.76/10万,累积率(0~74岁)为3.38%。农村地区中标发病率是城市地区的1.10倍、死亡率是城市地区的1.05倍。男性中标发病率是女性的2.28倍、死亡率是女性的2.51倍。肺癌年龄别发病率和死亡率均随年龄增加而上升,在85+岁组达到峰值。2010—2017年河南省肺癌中标发病(死亡)率整体均呈平稳趋势,农村男性中标死亡率呈显著上升趋势(APC=2.0%,95%CI:1.2%~2.7%)。[结论]河南省肺癌疾病负担居全部恶性肿瘤首位,发病率与死亡率均未出现下降趋势,应继续加强肺癌防控,推进筛查与早诊早治等工作。

[Purpose]To estimate the incidence and mortality of lung cancer in Henan Province in2017,and to analyze its trend from 2010 to 2017.[Methods]The qualified data of lung cancer from 2010 to 2017 were collected from Henan Cancer Registration and Follow-up System.Combined with the census data,the incidence,mortality,age-standardized rate by Chinese standard population(ASR China),age-standardized rate by world standard population(ASR world),and cumulative incidence(0~74 years old)of lung cancer were estimated by urban and rural,gender and age groups.The annual percentage change(APC)and its 95%confidence interval(CI)of ASR China from 2010 to 2017 were analyzed.[Results]In 2017,it was estimated that there were 58749 new cases of lung cancer in Henan Province,accounting for 20.27%of new cases of all cancers.The crude incidence rate of lung cancer was 54.27/105,with the ASR China of 39.20/105 and ASR world of 39.30/105.The cumulative incidence rate(0~74 years old)was 4.75%.It was estimated that there were 45921 deaths from lung cancer,accounting for 24.92%of all cancer deaths.The crude mortality rate was 42.42/105,with the ASR China of 29.58/105 and ASR world of29.76/105.The cumulative mortality rate(0~74 years old)was 3.38%.Subgroup analysis showed that the incidence of ASR China was 1.10 times in rural areas as that in urban areas,and it was2.28 times in males as that in females.The mortality of ASR China was 1.05 times in rural areas as that in urban areas,and it was 2.51 times in males as that in females.The age-specific incidence and mortality of lung cancer increased gradually with the increase of age,and reached the peak at age of 85+years old.From 2010 to 2017,the ASR China for mortality of lung cancer in Henan showed a steady trend,while an upward trend was observed in the mortality rate in rural males(APC=2.0%,95%CI:1.2%~2.7%).[Conclusion]The incidence and mortality of lung cancer rank first among all malignant tumors and are not decreased in Henan Province.It is necessary to strengthen the prevention and control of lung cancer,especially to carry out screening programs for early diagnosis and treatment.