回眸中医药超分子化学研究十载,构筑中医药超分子“气析”理论

Review of the TCM supramolecular chemistry research for 10 years and construct TCM supramolecular"Qi chromatography"theory

回眸中医药超分子化学研究历程,梳理和阐明怎样由中医药理论现代化所面临的问题推论出中医药超分子化学的破解之策,由此建立中医药超分子“气析”理论,找准现代化研究方法学大门。置自然界生物演化的大背景中来考虑,中医药理论是古代医家对生命体微观物质运行规律的宏观总结,本质上是对人体与自然界“分子社会”信息交流管控规律的揭示,常采用人文社会科学语言来表述医学科学的运行规律,具人文自然交融特质,是最典型的交叉学科。若要破解,就必须从现代自然科学中去寻觅既具有人文社会自然交融属性,又能反映生命体本质演化规律的学科,这便是生物超分子化学。为此,本团队于2011年展开了中医药理论、经络、药性、药理、品种归属、炮制、药剂、质量等超分子化学研究,完整提出了中医药学科发展面临的3个重大科学前沿问题和3个重大工程技术难题的破解之策,继而总结形成了现代化的中医药超分子“气析”理论诠释体系。

This paper systematically reviews the course of traditional Chinese medicine(TCM)supramolecular chemistry research,to comb and clarify how to deduce the solution that is found TCM supramolecular chemistry from the problems faced by the modernization of TCM theory,so as to establish TCM supramolecular"Qi chromatography"theory,which will consequently found as the correct door opened to the research methodology for the systematical modernization of TCM.Being considered the background of biological evolution in nature,the theory of TCM is a macro summary of the micro material operation law of life for the ancient doctors.In essence,it is a revelation of the interaction law of"molecular society"between human body and nature,which often used to expressing the operation law of natural life science with the language of humanities and social sciences,with the characteristics of blending humanities and nature,and with the interdisciplinary.However,in order to solve the problem of modernization of TCM theory,it is necessary to find a discipline with the attribute of human,society and nature from modern natural science,and which can reflect the essential law of the evolution of life body,and that is biological supramolecular chemistry.Hence,our team started the exploratory research on the modern interpretation of TCM theoretical supramolecular chemistry,such as the basic theory of TCM,meridian,drug properties,pharmacology,variety attribution,processing,pharmaceutics and quality control,etc.in 2011,gradually expounded the solutions to three major scientific frontier problems and three major engineering and technical problems in the development of TCM,and finally had established a modern interpretation system of TCM supramolecular"Qi chromatography"theory.