双网络Au NCs/HA/PVA复合水凝胶的荧光示踪性能和力学性能

Fluorescent Tracing Abilities and Mechanical Properties of Au NCs/HA/PVA Composite Hydrogel

以聚乙烯醇(PVA)为原料、金纳米簇(Au NCs)和纳米羟基磷灰石(HA)为掺杂物、戊二醛作为交联剂,用化学交联法和循环冷冻-解冻法制备双网络Au NCs/HA/PVA复合水凝胶并检测其荧光特性、力学性能和溶胀率,研究了Au NCs含量和冷冻-解冻循环次数对其性能的影响。结果表明:这种凝胶具有较好的荧光特性;Au NCs与PVA的质量比为2.6%和冷冻-解冻循环次数为9次时,这种凝胶的力学性能最优并具有显著的荧光性能,其拉伸弹性模量、断裂强度以及断裂能分别达到63.09 kPa、152.84 kPa和130.36 k J·m^(-3),含水率约为80%,与人体软骨组织的含水率相近。

Composite hydrogel of Au NCs/HA/PVA with double network was prepared by means of chemical crosslinking and cyclic freezing-thawing with polyvinyl alcohol(PVA)as raw material,gold nanocluster(Au NCs)and hydroxyapatite(HA)as dopants,and glutaraldehyde as crosslinking agent.The effect of Au NCs content and the number of freezing-thawing cyclics on the physical properties of Au NCs/HA/PVA composite hydrogels was investigated.The results show that the mechanical strength of the gels increased with the increasing number of the freezing-thawing cycles.When the Au NCs content is 2.6%and the number of the freezing-thawing cyclic is 9,the gel has the optimized mechanical proper-ties.The elastic modulus,breaking strength and fracture energy of the gel are 63.09 kPa,152.84 kPa and 130.36 k J·m^(-3),respectively.The moisture content is about 80%,which is similar to the human carti-lage tissue,and shows remarkable fluorescence properties.