进展性脑卒中患者肺部感染危险因素分析

Risk factors for pulmonary infection in patients with progressive stroke

目的探讨进展性脑卒中患者合并肺部感染的危险因素。方法收集2018年6月至2020年12月河南大学第一附属医院收治的236例进展性脑卒中患者的临床资料,根据患者是否合并肺部感染将患者分为感染组(n=61)和非感染组(n=175),分析进展性脑卒中患者发生肺部感染的危险因素。结果进展性脑卒中患者的年龄、脑卒中类型、吞咽困难、意识障碍、合并基础疾病、卧床时间及应用抗菌药物与合并肺部感染有关(P<0.05);患者的性别与合并肺部感染无关(P>0.05)。Logistic回归分析结果显示,年龄≥70岁、合并基础疾病、吞咽困难、意识障碍、卧床时间≥10 d是进展性脑卒中患者合并肺部感染的危险因素(P<0.05);疾病类型为脑出血、应用抗菌药物与进展性脑卒中患者合并肺部感染无关(P>0.05)。结论高龄、合并基础疾病、吞咽困难、意识障碍、长期卧床是进展性脑卒中患者发生肺部感染的危险因素,应提早采取干预措施预防肺部感染。

Objective To explore the risk factors for pulmonary infection in patients with progressive stroke.Methods The clinical data of 236 patients with progressive stroke treated in the First Affiliated Hospital of Henan University from June 2018 to December 2020 were collected.The patients were divided into infection group(n=61)and non-infection group(n=175)according to whether the patients complicated with pulmonary infection.The risk factors of pulmonary infection in patients with progressive stroke were analyzed.Results The age,stroke type,dysphagia,disturbance of consciousness,combined with basic diseases,the time of bed rest and the use of antibiotics of patients were related to pulmonary infection(P<0.05);the gender of patients was not related to pulmonary infection(P>0.05).Logistic regression analysis showed that age≥70 years old,combined with basic diseases,dysphagia,disturbance of consciousness and the time of bed rest≥10 d were the risk factors of pulmonary infection in patients with progressive stroke(P<0.05);the disease type was intracerebral hemorrhage,the use of antibiotics were not related to pulmonary infection in patients with progressive stroke(P>0.05).Conclusion Old age,complicated with basic diseases,dysphagia,disturbance of consciousness and long-term bed rest are the risk factors of pulmonary infection in patients with progressive stroke.Early intervention measures should be taken to prevent pulmonary infection.