妊娠新发完全性房室传导阻滞的病因及治疗进展

Progress in etiology and treatment of complete atrioventricular block detected for the first time during pregnancy

妊娠新发完全性房室传导阻滞是一种罕见且存在潜在母儿危险的疾病,至今病因不明,大多数学者认为其为先天性心脏传导阻滞所致。随着心脏起搏技术的发展,对有症状的完全性房室传导阻滞孕产妇放置心脏起搏器是首选的治疗方法,但对无症状孕产妇是否放置心脏起搏器治疗尚存在争议;抗心律失常药物一定程度上可作为放置心脏起搏器前的过渡用药;免疫治疗对妊娠新发完全性房室传导阻滞患者而言或许是一个避免放置起搏器的新策略。本文就妊娠新发完全性房室传导阻滞的病因及治疗进行综述,希望为此类患者的围产期管理及治疗提供参考。

Complete atrioventricular block(CAVB)detected for the first time during pregnancy is a rarely disease with potential maternal and fetal risk.The etiology is still unknown.Most scholars believe that it is caused by congenital heart block.With the development of pacing technology,pacemakers become the first choice for those pregnant women with symptomatic complete atrioventricular block,but whether to giving a pacemaker for those asymptomatic women remains debatable.Antiarrhythmic drugs can be used as a transitional drug before pacemaker placement.Immunotherapy may be a novel strategy for avoiding pacemaker placement in pregnant women with congenital complete atrioventricular block.This article summaries the etiology and treatment of complete atrioventricular block detected for the first time during pregnancy,hoping to provide reference for the perinatal management and treatment of this kind of patients.