脓疱型银屑病诊疗中国专家共识(2022版)

Diagnosis and treatment of pustular psoriasis:a Chinese expert consensus statement(2022)

脓疱型银屑病是银屑病的特殊类型,临床表现以红斑基础上的无菌性脓疱为特征,病因涉及遗传、免疫及感染等多种因素。脓疱型银屑病分为局限性和泛发性两个主要亚型。局限性脓疱型银屑病以外用药物治疗为主,疗效欠佳者可采用系统治疗和光疗;泛发性脓疱型银屑病通常需要系统治疗,可联合外用药物治疗和光疗。在国内外最新指南及共识的基础上,结合我国的诊疗现状,本专家委员会重点在脓疱型银屑病的临床表现及分型、辅助检查、诊断标准和治疗等方面形成共识,以进一步形成规范化诊疗模式。

Pustular psoriasis is a special type of psoriasis,characterized by aseptic pustules on an erythematous base.Its etiology involves multiple factors such as heredity,immunity and infection.Pustular psoriasis can be classified into 2 subtypes:localized and generalized pustular psoriasis.Localized pustular psoriasis is mainly managed with topical treatment,and patients with poor response to topical treatment can be treated with systemic therapy and phototherapy;generalized pustular psoriasis is usually treated with systemic therapy,which can be combined with topical treatment and phototherapy.Based on the latest Chinese and international guidelines and consensus,and combined with the current status of diagnosis and treatment of pustular psoriasis in China,the working group established this expert consensus,with an emphasis on clinical manifestations,classification,laboratory examinations,diagnostic criteria,and treatment of pustular psoriasis,so as to further develop a standardized model for diagnosis and treatment of pustular psoriasis.