摘要
AIM:To assess intraocular pressure(IOP)during the daily curve of intraocular pressure(DCPo)in keratoconic eyes and compare Goldmann applanation tonometer(GAT),without and with astigmatism correction(n GAT and c GAT)and Tono-Pen AVIA(TPA)assessment methods.METHODS:Thirty-nine keratoconic eyes of 24 patients were assessed.DCPo was evaluated with five IOP measurements;four were performed with a GAT(n GAT and c GAT),and a Tono-Pen AVIA(TPA)at various times throughout the day.RESULTS:Mean IOP DCPo values(mm Hg)were:n GAT,9.9±2.6;c GAT,11.3±2.6;TPA 12.3±3.1.Mean IOP DCPo differences(mm Hg)and Spearman’s correlation coefficients were as follows:c GATc-n GAT,1.32±1.31,r_(s)=0.879(P<0.01);c GAT-TPA,-1.02±2.08,r_(s)=0.723(P<0.01);and n GAT-TPA,-2.35±2.23,r_(s)=0.730(P<0.01).Bland-Altman analysis for agreement between c GAT-TPA and n GAT-TPA mean IOP DCPo measurements revealed a mean difference of 1.02(95%CI,0.35-1.70)and 2.35(95%CI,1.62-3.07)mm Hg,respectively.Regression analysis yielded the following equation:TPA IOP=5.49+0.775×c GAT-0.015×ACD-0.299×corneal astig matism,which allowed us to infer TPA IOP values from other parameters.CONCLUSION:In keratoconic eyes,IOP peaks of DCPo measurements are identified at 6 a.m.,independent of the tonometer.The mean DCPo values are:TPA>c GAT>n GAT.IOP TPA measures are predictive of c GAT values,adjusted according to anterior chamber depth and corneal astigmatism.
