围绝经期女性椎体及椎旁肌脂肪IDEAL-IQ定量研究

The application of IDEAL-IQ on the fat content of vertebrae bone marrow and paraspinal muscles in perimenopausal women

目的探讨IDEAL-IQ技术评估围绝经期女性腰椎椎体骨髓及椎旁肌脂肪含量定量分析价值。方法选取2017年1月~2019年12月来福建医科大学附属泉州第一医院进行健康体检的围绝经期女性80例为研究对象,进行腰椎IDEAL-IQ扫描。根据绝经时间,将受检者分为未绝经、0年<绝经时间≤5年、5年<绝经时间≤10年、绝经时间>10年四组,每组各20人。采用单因素方差分析比较不同分组腰椎椎体脂肪百分比(FF_(v))及双侧椎旁肌脂肪百分比(FF_(Lm)、FF_(Rm));年龄、绝经时间与FF_(v)、FF_(Lm)、FF_(Rm)值分别进行Pearson相关分析。结果不同围绝经期组患者FF_(v)、FF_(Lm)、FF_(Rm)值比较,差异均有统计学差异(P<0.05)。年龄与腰椎FF_(v)、FF_(Lm)、FF_(Rm)值均呈正相关(r=0.523、0.767、0.775;P均<0.001);绝经时间与腰椎FF_(v)、FF_(Lm)、FF_(Rm)值均呈正相关(r=0.490、0.742、0.741;P均<0.001)。结论IDEAL-IQ技术可定量评估围绝经期女性腰椎椎体骨髓及椎旁肌脂肪含量,对揭示绝经时间与椎体骨髓及椎旁肌脂肪含量的关系具有重要的指导价值。

Objective To assess the significance of IDEAL-IQ in quantitative evaluation of lumbar vertebral bone marrow and paraspinal muscle fat compositions in perimenopausal women.Methods IDEAL-IQ scans were performed on the lumbar spine in 80 volunteers.According to the time of menopause,the subjects were divided into the four groups:non-menopausal,0 years<menopausal time≤5 years,5 years<menopausal time≤10 years,and menopausal time>10 years.One-way analysis of variance was used to compare the lumbar vertebral marrow fat percentage FF_(v) and bilateral paraspinal muscle fat percentage FF_(Lm) and FF_(Rm) values in different groups.Pearson correlation analysis was performed on age,menopausal time and FF_(v),FF_(Lm) and FF_(Rm) values,respectively.Results The FF_(v),FF_(Lm) and FF_(Rm) values of different perimenopausal groups were statistically different(all P<0.05).Age was positively correlated with FF_(v),FF_(Lm) and FF_(Rm) values(r=0.523,r=0.767,r=0.775,all P<0.001).Menopausal time was positively correlated with FF_(v),FF_(Lm) and FF_(Rm) values(r=0.490,r=0.742,r=0.741,all P<0.001).Conclusion IDEAL-IQ technology can quantitatively assess the fat content of lumbar vertebral bone marrow and paraspinal muscles in perimenopausal women,and has important guiding value in revealing the relationship between menopause time and the fat content of vertebral bone marrow and paraspinal muscles.