肺心康胶囊对痰瘀阻肺型慢性肺源性心脏病的临床疗效

Clinical Effect of Feixinkang Capsule on Chronic Pulmonary Heart Disease with Phlegm and Blood Stasis Obstructing Lung-Type

目的:观察肺心康胶囊对痰瘀阻肺型慢性肺源性心脏病的临床疗效及对患者血气的影响。方法:选取益阳市第一中医医院2016年12月至2019年3月期间收治的40例痰瘀阻肺型慢性肺源性心脏病患者,按照入院顺序分为观察组和对照组,各20例。对照组给予西医常规治疗。观察组在对照组的基础上给予肺心康胶囊。评价两组患者综合疗效、血气分析等疗效性指标。结果:观察组临床控制占比高于对照组,差异具有统计学意义(P<0.05);治疗后观察组动脉血二氧化碳分压低于对照组,动脉血氧分压高于对照组,差异具有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05);治疗后两组患者的补体C3、E-玫瑰花环形成率均有不同程度升高,且治疗后观察组补体C3、E-玫瑰花环形成率均高于对照组,差异具有统计学意义(P<0.05)。结论:肺心康胶囊结合西医治疗方案能提高临床综合疗效,改善患者症状、体征。

Objective To observe the clinical effect of Fexinkang capsule on chronic pulmonary heart disease with phlegm and blood stasis obstructing lung-type and its effect on blood gas.Methods A total of 40 patients with chronic pulmonary heart disease of phlegm and blood stasis obstructing lung type were selected from Yiyang First Hospital of Traditional Chinese Medicine from December 2016 to March 2019.They were divided into observation group and control group according to the order of admission,with 20 cases in each group.The control group was given conventional western medicine treatment.The observation group was given Feixinkang capsule on the basis of the control group.The comprehensive curative effect,blood gas analysis and other curative effect indexes of the two groups of patients were evaluated.Results The proportion of clinical control in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the arterial blood carbon dioxide partial pressure in the observation group was lower than that of the control group,and the arterial blood oxygen partial pressure was higher than that of the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients(P>0.05).After treatment,the complement C3 and E-rosette formation rates in the two groups were increased to varying degrees,and the complement C3 and E-rosette formation rates in the observation group were higher than those in the control group after treatment,and the differences were statistically significant(P<0.05).Conclusion Feixinkang capsule combined with western medicine treatment can improve the comprehensive clinical efficacy and improve the symptoms and signs of patients.