SBRT与胸腔镜手术治疗早期非小细胞肺癌疗效比较

Comparison of the Efficacy of SBRT and Thoracoscope Surgery in the Treatement of Early Non-Small-Cell Lung Carcinoma

目的:比较立体定向放射治疗(SBRT)与胸腔镜手术治疗早期非小细胞肺癌(NSCLC)疗效。方法:选择2015年1月至2018年12月在洛阳市第三人民医院治疗的早期NSCLC患者42例,随机分为两组,SBRT组(21例)采取SBRT,胸腔镜治疗组(21例)采取胸腔镜手术治疗,分析比较两组患者1、2、3年总生存率(OS)与无病生存率(DFS)。结果:SBRT组和胸腔镜治疗组1、2、3年OS和DFS比较,差异均无统计学意义(P>0.05)。结论:胸腔镜手术治疗和SBRT对早期NSCLC的临床疗效相当,通常情况下二者均可作为早期NSCLC的主要治疗手段。但对于患者不愿手术或有手术禁忌证,SBRT可作为首选治疗方法。

Objective To compare the curative effect of stereotactic body radiotherapy(SBRT)and thoracoscopy surgery on early non-small cell lung cancer(NSCLC).Methods 42 patients with early NSCLC treated in Luoyang Third People’s Hospital from January 2015 to December 2018 were selected.The patients were divided into two groups:SBRT group with 21 cases received SBRT,thoracoscopic surgery group wih 21 cases received thoracoscopic surgery therapy,and the 1.2.3-year overall survival rate(OS)and disease-free survival rate(DFS)were analyzed and evaluated between the two groups.Results There was no significant difference in OS and DFS between the SBRT group and the thoracoscopic surgery group(P>0.05).Conclusion Thoracoscopic surgery therapy and SBRT have similar clinical efficacy for early NSCLC,and both are usually the primary treatment for early NSCLC.However,SBRT can be used as the first choice for patients who are unwilling or contraindicated for surgery.