高龄腹膜假黏液瘤患者术后发生并发症的影响因素

Risk Factors of Postoperative Complications in Elderly Patients with Pseudomyxoma Peritonei

目的:观察高龄腹膜假黏液瘤(pseudomyxoma peritonei,PMP)患者术后发生并发症情况并分析其影响因素。方法:选取2008年1月-2019年12月在航天中心医院黏液瘤科接受手术治疗的86例高龄PMP患者的临床资料进行回顾性分析,统计术后并发症发生率。采用多因素logistic回归分析高龄PMP患者术后并发症发生的危险因素。结果:86例高龄PMP患者中有32例患者术后出现并发症,发生率为37.2%。性别、年龄及是否接受腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)与高龄PMP患者术后发生并发症无关,差异均无统计学意义(P>0.05)。术后发生并发症者手术未达到根治、既往有腹腔手术史及白蛋白水平<30 g/L比例均高于术后未发生并发症者,差异均有统计学意义(P<0.05)。多因素logistic回归分析显示,手术未达到根治、既往有腹腔手术史、白蛋白水平<30 g/L均为高龄PMP患者术后发生并发症的危险因素(P<0.05)。结论:高龄PMP患者术后并发症发生率较高,且危险因素较多,应对加强对上述因素的监测与干预。

Objective:To investigate the postoperative complications of pseudomyxoma peritonei (PMP) in elderly patients and analyze the influencing factors.Method:The clinical data of 86 elderly PMP patients who received surgical treatment in Myxoma Department of Aerospace Center Hospital from January 2008 to December 2019 were retrospectively analyzed,and the incidence of postoperative complications was statistically analyzed.Multivariate logistic regression was used to analyze the risk factors of postoperative complications in elderly PMP patients.Result:Postoperative complications occurred in 32 cases of the 86 elderly PMP patients,with an incidence of 37.2%.Gender,age and whether hyperthermic intraperitoneal chemotherapy (HIPEC) were not associated with postoperative complications in elderly PMP patients,and there were no statistical significance (P>0.05).The proportions of surgery without radical treatment,previous abdominal surgery history and albumin level <30 g/L in patients with postoperative complications were higher than those without postoperative complications,with statistical significance (P<0.05).Multivariate logistic regression analysis showed that the risk factors for postoperative complications in elderly PMP patients were surgery without radical treatment,previous abdominal surgery history and albumin level <30 g/L (P<0.05).Conclusion:Elderly PMP patients have a high incidence of postoperative complications and many risk factors,so the monitoring and intervention of these factors should be strengthened.