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糖尿病视网膜病变与眼房水细胞因子相关性研究 被引量：3

CORRELATION BETWEEN DIABETIC RETINOPATHY AND CYTOKINE IN AQUEOUS HUMOR
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摘要 糖尿病视网膜病变包括视网膜微血管瘤、渗出以及视网膜增殖性改变。越来越多研究证明细胞因子参与其病情发展,为抗细胞因子药物的应用提供理论依据。本文就目前细胞因子与糖尿病视网膜病变研究进行综述。 Diabetic retinopathy includes retinal microangioma, exudation and retinal proliferative changes.More and more studies have shown that cytokines are involved in disease progression.It provides theoretical basis for the application of anti-cytokine drugs.This paper reviews the current studies on cytokines and diabetic retinopathy.
作者 甄琪 史桂桃 ZHEN Qi;SHI Guitao(The Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050 China)
机构地区 内蒙古医科大学附属医院验光配镜部
出处 《内蒙古医科大学学报》 2021年第6期656-659,共4页 Journal of Inner Mongolia Medical University
基金 内蒙古自治区教育科学研究“十三五”规划课题(NGJGH2020289)。
关键词 糖尿病视网膜病变 眼房水 细胞因子 diabetic etinopathy aqueous humor cytokine
分类号 R774 [医药卫生—眼科]
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  • 1Kern TS.Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy.Exp Diabetes Revs 2007;2007:95103.
  • 2Khalfaoui T,Lizard G,Ouertani-Meddeb A.Adhesion molecules (ICAM-1 and VCAM-1) and diabetic retinopathy in type 2 diabetes.J Mol Histol 2008;39(2):243-249.
  • 3Goldberg RB.Cytokine and cytokine-like inflammation markers,endothelial dysfunction,and imbalanced coagulation in development of diabetes and its complications.J Clin Endocrinal Metab 2009;94(9):3171-3182.
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  • 5Gustavsson C,Agardh CD,Zetterqvist AV,Nilsson J,Agardh E,Gomez MF.Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.PLoS One 2010:5(9):e12699.
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  • 7McLeod DS,Lefer DJ.Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.Am J Pathol 1995;147(3):642-653.
  • 8Limb GA,Hickman-Casey J,Hollifield RD,Chignell AH.Vascular adhesion molecules in vitreous from eyes with proliferative diabetic retinopathy.Invest Ophthalmol Vis Sci 1999;40(10):2453-2457.
  • 9Hernandez C,Burgos R,Canton A,García-Arumí J,Segura RM,Simó R.Vitreous levels of vascular cell adhesion molecule and vascular endothelial growth factor in patients with proliferative diabetic retinopathy:a case-control study.Diabetes Care 2001;24(3):516-521.
  • 10Tang S,Le-Ruppert KC,Gabel VP.Expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on proliferating vascular endothelial cells in diabetic epiretinal membranes.Br J Ophthalmol 1994;78:370-376.

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内蒙古医科大学学报
2021年 第6期

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