莫西沙星注射液致低血钾1例分析

One case of hypokalemia caused by moxifloxacin injection and literature analysis

目的探讨莫西沙星注射液致低血钾的机制,为临床安全合理使用莫西沙星提供参考。方法分析该患者接受莫西沙星注射液治疗后发生低血钾的诊疗过程。结果患者静脉滴注莫西沙星注射液1周后出现低血钾(2.78 mmol·L^(-1)),予停用莫西沙星注射液,静脉及口服补钾后,血钾恢复(4.41 mmol·L^(-1))。结论静脉滴注莫西沙星注射液可能导致低血钾,治疗中应予以重视。

Objective To explore the mechanism by which hypokalemia is caused by moxifloxacin injection so as to provide reference for clinical rational and safe use of moxifloxacin.Methods The diagnosis and treatment process of one case of hypokalemia after moxifloxacin injection was analyzed.Results Symptoms of hypokalemia(2.78 mmol·L^(-1))occurred one week after intravenous injection of moxifloxacin.After moxifloxacin injection was withdrawn and intravenous and oral potassium supplementation was started,the level of potassium returned to normal(4.41 mmol·L^(-1)).Conclusion Intravenous injection of moxifloxacin may lead to hypokalemia,which deserves more attention in clinic.