俯卧位通气对36例危重型COVID-19患者的影响

Effects of prone position ventilation on 36 cases of severe COVID-19 patients

目的:分析俯卧位通气(PPV)对36例危重型新型冠状病毒肺炎(COVID-19)患者的影响。方法:收集武汉市肺科医院重症监护室行PPV的36例危重型COVID-19患者,分析其PPV前后动脉血气指标及呼吸力学指标改变情况。结果:与PPV前相比,PPV后气道峰压及气道平台压下降(P<0.01)、SaO_(2)和PaO_(2)上升(P<0.01),但呼吸频率、潮气量及肺顺应性差异无统计学意义(P>0.05)。PPV后第1 d与PPV前、PPV后第3 d与PPV后第1 d相比,FiO_(2)均下降、PaO_(2)/FiO_(2)均增加(P<0.01)。结论:俯卧位通气可改善COVID-19患者的呼吸状况,提高患者的氧合指数。

Objective:To analyze the effects of prone position ventilation(PPV)on 36 cases of severe COVID-19 patients.Methods:36 severe COVID-19 patients receiving PPV in the intensive care unit of Wuhan Pulmonary Hospital were collected and analyzed for changes in arterial blood gas and respiratory mechanics indexes before and after PPV.Results:After PPV,peak airway pressure and airway plateau pressure were decreased significantly(P<0.01),SaO_(2)and PaO_(2)were increased significantly(P<0.01),but respiratory rate,tidal volume,and lung compliance had no significant differences(P>0.05)compared with those before PPV.FiO_(2)was significantly decreased and PaO_(2)/FiO_(2)was significantly increased on the first day after PPV and the third day after PPV in patients compared with those before PPV and on the first day after PPV,respectively(P<0.01).Conclusion:PPV can improve breathing and increase the oxygenation index of COVID-19 patients.