2,5-呋喃二甲酸合成新技术及应用进展

Development of 2,5-furandicarboxylic acid synthesis technology and application prospect

2,5-呋喃二甲酸(FDCA)作为一种重要的生物基平台化合物,是制备生物基呋喃二甲酸乙二醇酯(PEF)材料的关键中间体,应用前景良好。介绍了当前FDCA合成技术的新路线、新工艺,包括化学-酶氧化法、醛糖酸法、荷兰Avantium公司YXY技术、全细胞生物转化法、电催化氧化法、光催化氧化法及其他改进方法,并结合当前生物质资源的利用及可降解材料的发展态势,对FDCA产品的应用前景进行分析。提出FDCA合成的技术难点主要在于高效催化氧化催化剂及其体系的开发,通过构建反应机理与催化剂构效,可开发环保、高效、低成本的FDCA合成技术。

As an important biobased platform compound,2,5-furandicarboxylic acid(FDCA)is a key intermediate monomer for the preparation of biobased 2,5-furardigarate glycol polyester(PEF)materials,which has a promising application prospect.In this paper,new synthesis routes and processes of FDCA are introduced,including chemical-enzymatic oxidation method,aldonic acid method,YXY technology from the Netherlands Avantium,whole-cell biological catalysis,electrocatalytic oxidation,photocatalytic oxidation and other improved methods.Also,application,market,and prospect of FDCA are analyzed considering the current utilization of biomass resources and the development trend of degradable materials.Finally,the technical difficulty of FDCA synthesis mainly lies in the development of a highly efficient catalytic-oxidation catalyst and its chemical system.By constructing reaction mechanisms and catalyst structure effects,the development of environmental protection,high efficiency,and low cost FDCA synthesis technology can be proposed.