动脉压力波形分析在麻醉诱导期的应用

Application of arterial pressure waveform analysis in anesthesia induction period

为探索动脉波形分析方法的临床意义,使用波形分离法与储存压力波模型对采集到的25例进行全麻手术的高龄患者的动脉压力波形进行波形分析,在获得P_(f)、P_(b)以及P_(e)、P_(r)等波形形态参数后,将诱导前后的参数变化量与临床生命指标变化量进行相关性分析。在本文的研究群体中,波形分离法与储存压力波模型的参数均与诱导中的血压和心率变化量有相关性,其中△P_(e)与临床指标△PP相关系数最高(r=0.926)。从生理病理学的角度对波形参数的变化进行解读,旨在探索波形分析在诱导期对全麻患者麻醉水平的应用价值,可为动脉压力波形分析及其应用提供新的理论基础和技术方案。

The arterial pressure waveforms of 25 elderly patients undergoing general anesthesia are decomposed by wave separation analysis and arterial reservoir model for clarifying the clinical significance of arterial waveform analysis.After obtaining the waveform parameters such as P_(f),P_(b) and P_(e),P_(r),etc.,the correlations between the variations of parameters before and after induction and the changes of clinical vital signs are analyzed.The parameters of wave separation analysis and arterial reservoir model are all related to the changes of blood pressure and heart rate during induction,and the correlation coefficient between△P_(e) and clinical index△PP is found to be the highest (r=0.926).In addition,the changes of waveform parameters are interpreted from the perspective of physiological pathology,aiming to explore the application value of waveform analysis in evaluating the anesthesia level during the induction period of general anesthesia,which can provide a new theoretical basis and technical scheme for the analysis of arterial pressure waveform and its application.