猫泛白细胞减少症疫苗的研究进展

Progress on Feline Panleukopenia Vaccine

猫泛白细胞减少症是一种由猫泛白细胞减少症病毒引起的,猫科动物常见的接触性传染病,临床发病率和死亡率均较高,疫苗免疫接种是预防和控制该病最经济、最直接的措施。然而,国内几无商业化宠物疫苗,特别是猫用疫苗,国外疫苗进口困难,亟需开发新型宠物用高效疫苗。对国内外猫泛白细胞减少症疫苗现状及不同类型疫苗(灭活疫苗、减毒活疫苗等)的优缺点进行了综述与分析,以期为我国猫泛白细胞减少症疫苗的研发提供参考。

Feline panleukopenia,caused by feline panleukopenia virus(FPV),is a highly contagious infectious disease that characterized by leucopenia and hemorrhagic gastroenteritis,which severely affects the health of cat or large wild Felidae.Vaccine immunization is the most economical and direct measurement to prevent and control the disease.However,there is almost no commercialized pet vaccine in domestic,especially for cats,so a highly effective vaccines for pet use were urgent needed.In this paper,the research status,the pros and cons about FPV vaccine,either domestic or abroad,which including inactivated vaccine,attenuated live vaccine and live vector vaccine were summarized,so as to provide some useful reference for subsequent study of vaccine against FPV.