易黄汤为基本方治疗女性生殖系统炎症的Meta分析

Meta analysis of Yihuang decoction reduction on inflammation of the female reproductive system

目的:评价以易黄汤为基本方治疗女性生殖系统炎症的临床疗效。方法:检索国内有关以易黄汤为基本方治疗女性生殖系统炎症的临床随机对照试验,包括CNKI、VIP、WFPD、CBM,依据严格的纳入标准及排除标准对所检索的文献进行筛选,提取有效数据,运用RenMan 5.3 Meta分析软件对资料进行分析。结果:最终有28篇随机对照试验被纳入,总计3478例患者。Meta分析结果显示,以易黄汤为基本方治疗女性生殖系统炎症的临床总有效率高于常规西药治疗组。(OR=5.46,95%CI[4.25,7.02],P<0.00001)。结论:以易黄汤为基本方或配合常规西药治疗女性生殖系统炎症总有效率高于常规西药治疗组。但是所纳入的研究质量普遍偏低,需要高质量的随机对照试验进行验证。

Objective:Evaluation of the clinical efficacy of treatment of inflammation of female reproductive system with the Yihuang decoction(易黄汤)as the basic method.Methods:To retrieve clinical randomized controlled trials on the treatment of inflammation of the female reproductive system in China,including the China Knowledge Network Database,the Wamp Journal Full Text Database,the Wanfang Database,the Chinese Biomedical Literature Database,screening the retrieved literature according to the criteria set and excluding the criteria,extracting the valid data,and using RenMan 5.3 software to analyze the literature.Results:Were eventually included in 28 randomized controlled trials,with a total of 3,478 patients.Meta analysis showed that the clinical effectiveness of the treatment of inflammation of the female reproductive system was higher than that of the conventional Western drug treatment group(OR equal 5.46,95%CI,7.02),P<0.00001).Conclusion:The treatment of inflammation of the female reproductive system with the Yihuang decoction as the basic prescription is higher than that of the conventional Western medicine treatment group.However,the quality of the studies included is generally low and requires high-quality randomized controlled trials.