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EBV阳性胃淋巴上皮瘤样癌的诊治进展

Advance in diagnosis and treatment of Epstein-Barr virus positive lymphoepithelioma-like gastric carcinoma
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摘要 胃淋巴上皮瘤样癌(lymphoepithelioma-like gastric carcinoma,LELGC)是一类罕见的胃癌,占胃癌的1%~4%[1],其具有独特的临床病理特征,包括伴淋巴细胞广泛浸润、肠型胃癌多见、中老年男性多发、好发于近端胃和残胃等[2]。1976年,该肿瘤的病理形态特征首次被报道,作者将其描述为伴有淋巴间质的癌[3]。2010年WHO消化道肿瘤分类建议,使用"伴有淋巴样间质的胃癌"为其命名,并被将其单独列出[4]。LELGC分为2个亚型,即EB病毒(Epstein-Barr Virus,EBV)感染阳性癌和高频微卫星不稳定性癌。
作者 崔芷萌 任刚 蔡嵘 CUI Zhimeng;REN Gang;CAI Rong
出处 《诊断学理论与实践》 2021年第5期502-506,共5页 Journal of Diagnostics Concepts & Practice
基金 上海交通大学医学院科研基金(09XJ21013) 上海市卫生局科研基金(2010029 and 2010057) 上海市科学技术委员会科研基金(124119a0300) 上海市教育委员会科研基金(12Y2034)。
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