老年冠心病病人自我效能水平与药物素养及服药依从性的相关性

Relationship of self-efficacy with drug literacy and medication compliance in elderly patients with coronary heart disease

目的探讨自我效能水平在老年CHD病人药物素养与服药依从性间的中介作用。方法选取2021年2~3月中国科学技术大学附属第一医院南区心内科收治且接受经皮冠状动脉介入治疗的86例老年CHD病人作为研究对象。采用自制一般资料调查问卷、自我效能量表、药物素养量表及服药依从性量表进行调查。结果86例老年CHD病人自我效能总分为(29.33±7.33)分;服药依从性总分为(4.34±1.57)分;药物素养总分为(4.64±1.46)分。老年CHD病人自我效能水平与药物素养呈正相关(r=0.369,P<0.01);药物素养、自我效能均与服药依从性呈正相关(r=0.489、0.551,P<0.01)。经Bootstrap检验结果表明,自我效能水平在老年CHD病人药物素养与服药依从性中有显著的部分中介效应(β=0.16),且自我效能所占中介效应对总效应的贡献率为32.70%(0.16/0.49)。结论老年CHD病人药物素养对服药依从性具有正向预测作用,自我效能在药物素养与服药依从性间发挥部分中介效应,提示临床医护人员可通过提高病人的药物素养和自我效能方面改善病人的服药依从性。

Objective To explore the mediating effect of self-efficacy on drug literacy and medication compliance in the elderly patients with coronary heart disease(CHD).Methods From February to March 2021,86 elderly patients with CHD treated by percutaneous coronary intervention in the Department of Cardiology,the First Affiliated Hospital of University of Science and Technology of China were enrolled.All patients received the assessment of self-made general information questionnaire,self-efficacy scale,drug literacy scale and medication compliance scale.Results The total score of self-efficacy of the 86 elderly patients with CHD was 29.33±7.33;The total score of medication compliance was 4.34±1.57;The total score of drug literacy was 4.64±1.46.There was a positive correlation between self-efficacy and drug literacy in the elderly patients with CHD(r=0.369,P<0.01).Drug literacy and self-efficacy were positively correlated with medication compliance(r=0.489,0.551,P<0.01).Bootstrap test showed that self-efficacy level had a significant mediating effect on drug literacy and medication compliance in the elderly patients with CHD(β=0.16),and the contribution rate of mediating effect of self-efficacy to the total effect was 32.70%(0.16/0.49).Conclusions Drug literacy has a positive predictive effect on medication compliance in the elderly patients with CHD,and self-efficacy plays a partial mediating effect between drug literacy and medication compliance.It is suggested that clinical medical staff can improve the medication compliance of patients by improving their drug literacy and self-efficacy.