Synchronous colorectal liver metastases:therapeutic considerations

More than 50%of patients will develop colorectal cancer(CRC)liver metastases(CRCLM)during the course of their disease,while 15-25%of patients will have metastatic disease present at the time of initial diagnosis.Resection of CRCLM is possible in approximately one-in-four patients and 5-year overall survival(OS)rates have improved to nearly 60%in selected patients who undergo resection.