黑老虎木脂素化学成分及药理作用研究进展

Advances in chemical constituents and pharmacological activities of lignans from Kadsura coccinea

黑老虎是一种具有药用、食用、观赏等多种价值的经济植物。黑老虎的化学成分及药理作用研究进展较快,目前已分离出200余种化合物,其中木脂素类化合物121种,具有抗炎、抗肿瘤、抗HIV、抗凝血、抗氧化、保肝等多种药理作用。现对黑老虎中木脂素类化学成分和药理作用进行综述,为黑老虎的深入开发利用提供参考。

Kadsura coccinea is an economic plant with medicinal,edible,ornamental and other values.The research on chemical constituents and pharmacological effects of K.coccinea has achieved rapid progress.More than 200 compounds have been reported so far,including 121 lignans.These lignans have various pharmacological effects,such as anti-inflammatory,anti-tumor,anti-HIV,anti-coagulation,anti-oxidation,liver-protection,ect.The chemical constituents and pharmacological effects of lignans in K.coccinea are reviewed here to provide a reference for the further development and utilization.