摘要
Post-operative pancreatic fistula(POPF)is a common and dangerous complication of pancreatic resection,occurring in 5-30%of patients.It is a significant source of morbidity and mortality,leading to prolonged hospital stays and increased healthcare costs(1).The most widely accepted definition of POPF comes from the International Study Group on Pancreatic Fistula(ISGPF).Initially created in 2005,this classification system for POPF was revised in 2016 such that POPF should be associated with a clinically relevant change in status,deeming what was originally defined as a Grade A fistula as a biochemical leak and grade B and C fistulas as clinically relevant(CR)fistulae(Table 1)(2).