评分预测肝细胞癌术前肝储备功能的价值

Value of cholesterol combined with ALBI score in predicting liver reserve function before hepatocellular carcinoma surgery

目的探究血清总胆固醇(cholesterol)在肝细胞癌(HCC)行肝切除术患者在肝储备功能预测中的临床价值。方法回顾性分析2019年1月至2021年1月120例在湖北省十堰市太和医院接受肝癌切除术的HCC患者术前总胆固醇水平与白蛋白-胆红素(ALBI)分级及术后肝功能衰竭的关系。结果术前ALBI分级1级患者血清总胆固醇水平[(4.34±0.96)mmol/L]高于2级患者[(3.47±0.26)mmol/L]和3级患者[(2.40±0.21)mmol/L](P<0.05)。结论血清总胆固醇水平可以反映HCC患者术前肝功能损害程度和肝储备能力,可作为患者预后判断的参考依据。

【Objective】To investigate the clinical value of cholesterol in predicting liver reserve function of hepatocellular carcinoma(HCC)patients undergoing hepatocellular carcinoma resection.【Methods】A retrospective analysis was conducted on the relationship between preoperative total cholesterol level and ALBI(Albumin-bilirubin)grade and postoperative liver failure in120 HCC patients who underwent hepatocellular carcinoma resection in Taihe Hospital of Shiyan City from January 2019 to January2021.【Results】The serum total cholesterol level of patients with ALBI grade 1 before surgery was 4.34±0.96 mmol/L was significantly higher than that of grade 2 patients(3.47±0.26 mmol/L)and grade 3 patients(2.40±0.21 mmol/L),and the difference was statistically significant(P<0.05).【Conclusion】Serum total cholesterol level can reflect the degree of liver function damage and liver reserve capacity before operation in HCC patients,and can be used as a reference for prognosis judgment of patients.