肺癌合并脑梗死的相关危险因素分析

Analysis of the Related Risk Factors of Lung Cancer Combined with Cerebral Infarction

目的肺癌合并脑梗死的相关危险因素分析。方法回顾性分析收治的肺癌患者300例,按是否合并脑梗死分为A组(肺癌合并脑梗死,67例)和B组(肺癌未合并脑梗死,233例)。采用t和χ^(2)检验进行组件基线资料差异比较,采用logistics回归模型进行回归分析。结果肺癌合并脑梗死患者CA125、PLT、PNR、D-二聚体、AFP、CEA、CA199表达水平显著高于未合并脑梗死者(P<0.05);多因素logistics回归分析结果显示,PLT、PNR、CEA、CA125、CA199和D-二聚体为肺癌患者罹患脑梗死的独立危险因素(P<0.05)。结论肺癌可显著增加脑梗死发病率,PLT、PNR、CEA、CA125、CA199和D-二聚体为独立危险因素。

Objective To analyze the related risk factors of lung cancer combined with cerebral infarction.Methods 300 lung cancer patients were divided into group A(lung cancer with cerebral infarction,67 cases)and group B(lung cancer without cerebral infarction,233 cases).Assembly baseline data differences were compared using t and χ_(2) tests and regression analysis using logistics regression model.Results CA125,PLT,PNR,D-dimer,AFP,CEA,CA199 expression in patients with cerebral infarction were significantly higher than those without brain infarction(P<0.05);multi-factor logistics regression analysis showed that PLT,PNR,CEA,CA125,CA199 and D-dimers were independent risk factors for cerebral infarction in patients with lung cancer(P<0.05).Conclusion Lung cancer can significantly increase the incidence of cerebral infarction,PLT,PNR,CEA,CA125,CA199 and D-dimers are independent risk factors.