库欣病合并鞍区脊索瘤1例

Cushing’s disease complicated with chordoma in sellar region: a case report

目的 探讨促肾上腺皮质激素(ACTH)依赖性皮质醇增多症病人的诊断方法。方法 报告1例库欣病合并鞍区脊索瘤的病例,并进行相关文献分析。结果 对于ACTH依赖性皮质醇增多症病人的诊断,大剂量地塞米松抑制试验及垂体增强MRI不能明确定位时,垂体动态增强MRI及岩下窦采血可帮助进行定位诊断。结论 垂体动态增强MRI及岩下窦采血对于库欣病病人的定位诊断有一定价值。

Objective To investigate the diagnostic methods of patients with adrenocorticotropic hormone (ACTH) dependent hypercortisolism.Methods A case of Cushing’s disease complicated with sellaring chordoma was reported,and the relevant literature was analyzed.Results For the diagnosis of patients with ACTH-dependent hypercortisolism,when the localization diagnosis could not be clearly made through high-dose dexamethasone inhibition test and pituitary enhancement MRI,pituitary dynamic enhancement MRI and bilateral inferior petrosal sinus sampling could help to diagnose localization.Conclusion Pituitary dynamic enhancement MRI and bilateral inferior petrosal sinus sampling have certain value for the localization diagnosis of patients with Cushing’s disease.