胰岛素应用无针注射器与胰岛素笔皮下注射的比较

Comparison between Needle-free syringe and insulin pen for subcutaneous injection of insulin

胰岛素是治疗糖尿病的重要方式之一,而对于针头的恐惧以及低血糖、疼痛、瘀伤、出血、皮下脂肪增生等不良反应常常会阻碍病人启动或坚持使用胰岛素。因此,建立在胰岛素笔之上,一种新型的注射装置——无针注射器开始进入大众视野,旨在获得更好的血糖控制,延缓糖尿病慢性并发症的发生。现从工作原理、药理学特征及临床疗效、胰岛素注射的不良反应、注射体验、经济负担五个方面综合分析无针注射器相对于胰岛素笔皮下注射胰岛素的优缺点,多角度认识无针注射装置,从而为临床糖尿病的治疗提供一定的参考。

Insulin is one of the important ways to treat diabetes.Fear of needles and adverse reactions such as hypoglycemia,pain,bruises,bleeding,and subcutaneous fat hyperplasia often prevent patients from starting or sticking to insulin.Therefore,based on the insulin pen,a new type of injection device,a needle-free injection,has begun to enter the public’s field of vision,aiming to obtain better blood glucose control and delay the occurrence of chronic complications of diabetes.Now we will comprehensively analyze the advantages and disadvantages of needle-free injections compared to insulin pens with subcutaneous injection of insulin from five aspects:working principle,pharmacological characteristics and clinical efficacy,adverse reactions of insulin injection,injection experience,and economic burden,so as to provide a certain reference for the treatment of clinical diabetes.