健脾固肾法联合甘露聚糖肽胶囊防治小儿反复呼吸道感染的临床研究

Clinical Study of Invigorating Spleen and Strengthening Kidney Combined with Mannan Peptide Capsules in the Prevention and Treatment of Recurrent Respiratory Tract Infection in Children

目的:探讨健脾固肾法联合甘露聚糖肽胶囊防治小儿反复呼吸道感染的临床效果。方法:选取平顶山市中医医院2019年5月至2020年5月期间收治的100例反复呼吸道感染患儿,随机分为对照组和观察组,各50例。对照组服用甘露聚糖肽胶囊治疗,观察组采用健脾固肾法联合甘露聚糖肽胶囊进行治疗,观察两组患儿治疗前后免疫指标变化及症状改善情况。结果:治疗后两组患儿的各项中医证候积分有所降低,且观察组积分均低于对照组,差异具有统计学意义(P<0.05)。治疗后两组患儿的血清免疫球蛋白A(IgA)、IgG、IgM水平均有不同程度的提升,且观察组的IgA、IgG、IgM水平均高于对照组,差异具有统计学意义(P<0.05)。观察组患儿治疗总有效率为96.00%,高于对照组的84.00%,差异具有统计学意义(P<0.05)。结论:在小儿反复呼吸道感染的防治中采用健脾固肾法联合甘露聚糖肽胶囊进行治疗,能够明显改善患儿的症候症状,提高治疗总有效率。

Objective To investigate the clinical effect of invigorating spleen and strengthening kidney combined with mannan peptide capsule in the prevention and treatment of recurrent respiratory tract infection in children.Methods A total of 100 children with recurrent respiratory tract infection admitted to Pingdingshan Hospital of Traditional Chinese Medicine from May 2019 to May 2020 were randomly divided into a control group and an observation group,with 50 cases in each group.The control group was treated with mannan peptide capsule,and the observation group was treated with invigorating spleen and strengthening kidney combined with mannan peptide capsule.The changes of immune indexes and clinical symptom improvement in the two groups were observed before and after treatment.Results After treatment,the levels of immunoglobulin A(IgA),IgG and IgM in the two groups were improved to varying degrees,and the levels of IgA,IgG and IgM in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was 96.00%,higher than 84.00%of the control group,the difference was statistically significant(P<0.05).Conclusion In the prevention and treatment of recurrent respiratory tract infection in children,invigorating spleen and strengthening kidney combined with mannan peptide capsules can significantly improve the symptoms and improve the total effective rate of treatment.