连续性血液净化在重症监护病房中的应用

Application of Continuous Blood Purification in Intensive Care Unit

目的探讨对重症监护病房患者给予连续性血液净化干预后获得临床效果。方法将我院2016年8月至2019年4月收治的64例重症监护病房患者按照数字奇偶法分组;治疗组(32例):采用常规方法+连续性血液净化方法展开疾病治疗;对照组(32例):采用常规方法展开疾病治疗;对组间重症监护病房患者疗效数据、氧合指数、血尿素氮、血肌酐、体温、血pH值、APACHEⅡ(急性生理学及慢性健康状况评分系统)评分以及MODS(多器官功能障碍综合征)评分展开对比。结果治疗组重症监护病房疗效数据(96.88%)高于对照组(68.75%)(P<0.05);治疗组重症监护病房患者氧合指数(269.09±32.42)、血pH值(7.60±0.23)高于对照组(245.59±37.99)、(7.16±0.39),体温(36.30±0.43)℃、血尿素氮(13.41±3.09)mmol/L以及血肌酐(127.09±20.62)μmol/L低于对照组(38.79±1.29)℃、(24.02±3.25)mmol/L(285.06±36.96)μmol/L(P<0.05);治疗前,治疗组重症监护病房患者APACHEⅡ评分(29.25±2.55)分与对照组(29.31±2.56)分比较差异不明显(P>0.05);治疗后,治疗组APACHEⅡ评分(12.29±3.02)分低于对照组(20.31±3.05)分(P<0.05);治疗前,治疗组MODS评分(8.39±1.59)分同对照组MODS评分(8.31±1.11)分比较,未呈现出明显差异(P>0.05);治疗后,治疗组MODS评分(4.26±1.39)分均低于对照组MODS评分(5.99±1.51)分(P<0.05)。结论连续性血液净化方式的有效应用,可使得重症监护病房患者疗效数据获得显著提升,并且能够将氧合指数、血pH值显著提升,使得体温、血尿素氮以及血肌酐获得有效降低,最终使得重症监护病房患者综合状态获得有效提升,对于系列疾病症状进行有效改善,对患者脏器功能进行充分保护,最终实现重症监护病房患者生活品质提升以及有效预后。

Objective To investigate the clinical effect of continuous blood purification intervention on patients in intensive care unit.Methods 64 cases of icu patients admitted to our hospital from August 2016 to April 2019 were grouped by odd-even method.Treatment group(32 cases):conventional method+continuous blood purification method to carry out disease treatment;control group(32 cases):conventional treatment;efficacy data,oxygenation index,blood urea nitrogen,blood creatinine,body temperature,blood pH,APACHEⅡ(Acute Physiology and Chronic Health Status Scoring System)score and MODS(Multiple Organ dysfunction syndrome)score were compared between groups.Results The curative effect of icu in treatment group(96.88%)was higher than that in control group(68.75%)(P<0.05).Oxygenation index(269.09±32.42)and blood pH value(7.60±0.23)in the treatment group were higher than those in the control group(245.59±37.99)and(7.16±0.39).Body temperature(36.30±0.43)℃,blood urea nitrogen(13.41±3.09)mmol/L and blood creatinine(127.09±20.62)μmol/L were lower than those in control group(38.79±1.29)℃,(24.02±3.25)mmol/L and(285.06±36.96)μmol/L(P<0.05);before treatment,APACHEⅡscores of icu patients in treatment group(29.25±2.55)and control group(29.31±2.56)had no significant difference(P>0.05);after treatment,the APACHEⅡscore of the treatment group(12.29±3.02)was lower than that of the control group(20.31±3.05)(P<0.05).Before treatment,there was no significant difference in MODS score between the treatment group(8.39±1.59)and the control group(8.31±1.11)(P>0.05);after treatment,MODS score of the treatment group(4.26±1.39)was lower than that of the control group(5.99±1.51)(P<0.05).Conclusion The effective application of continuous blood purification way,can make patients with intensive care unit,data acquisition significantly increased,and can oxygenation index significantly increased,blood pH value,makes the body temperature,blood urea nitrogen and serum creatinine effectively reduce,eventually making general intensive care unit patients status was effective to ascend,for the series effectively improve symptoms,to fully protect patients viscera function,finally realizes the intensive care unit patients life quality promotion and effective outcome.