卡前列素氨丁三醇注射液与宫腔填纱对前置胎盘剖宫产产后出血的效果研究

Effect of Carboprost Tromethamine Injection and Intrauterine Gauze on Postpartum Hemorrhage after Cesarean Section with Placenta Previa

目的研究卡前列素氨丁三醇注射液与宫腔填纱对前置胎盘剖宫产产后出血的治疗效果。方法选取本院2016年5月至2018年3月收治的前置胎盘剖宫产产后出血产妇88例,按患者入院顺序分配组别,前44例产妇分为联合治疗组,后44例分为参照组,参照组产妇给予宫缩素及宫腔填纱,联合治疗组在宫腔填纱疗同时给予产妇卡前列素氨丁三醇注射液治,治疗期间记录产妇术后2 h、12 h、24 h出血量,评估两组产妇临床疗效并行组间对比,记录治疗后收缩压、舒张压、血氧饱和度、住院时间、恶露持续时间及不良反应发生率、产妇满意度评价情况。结果与对照组相比,联合治疗组治疗有效率显著更高(P<0.05),联合治疗组产后12 h、24 h出血量显著更低(P<0.05),两组产妇产后2 h出血量对比无显著差异(P>0.05);治疗后联合治疗组收缩压、舒张压显著低于参照组(P<0.05),血氧饱和度显著高于参照组(P<0.05),住院时间及恶露持续时间显著短于参照组(P<0.05);两组不良反应率对比无显著差异(P>0.05);满意度评价显著高于参照组(P<0.05)。结论在前置胎盘剖宫产产后出血治疗中给予产妇卡前列素氨丁三醇注射液与宫腔填纱可取得良好止血效果,可积极推广应用。

Objective To study the effect of capproxin amintriol injection and intrauterine yarn on cesarean bleeding of placenta previa.Methods Eighty eight pregnant women with postpartum hemorrhage after cesarean section of placenta previa treated in our hospital from May 2016 to March 2018 were divided into groups according to the order of admission.The first 44 pregnant women were divided into the combined treatment group and the last 44 were divided into the reference group.The pregnant women in the reference group were given oxytocin and intrauterine gauze filling,and the combined treatment group were given maternal carboprost aminobutanol injection at the same time,During the treatment period,the amount of maternal bleeding at 2 hours,12 hours and 24 hours after operation was recorded,the clinical efficacy of the two groups was evaluated,and the comparison between the two groups was made.The systolic blood pressure,diastolic blood pressure,blood oxygen saturation,length of hospitalization time,lochia duration,incidence of adverse reactions and evaluation of maternal satisfaction were recorded.Results Compared with the control group,the effective rate of the combined treatment group was significantly higher(P<0.05).The amount of postpartum hemorrhage in the combined treatment group was significantly lower at 12 hours and 24 hours(P<0.05).There was no significant difference in the amount of postpartum hemorrhage in the two groups(P>0.05).And the systolic and diastolic blood pressure in the combined treatment group were significantly lower than those in the reference group(P<0.05).The blood oxygen saturation was significantly higher than that in the reference group(P<0.05).And the hospitalization time and lochia duration in the combined treatment group were significantly shorter(P<0.05).There was no significant difference in adverse reaction rate between the two groups(P>0.05).The satisfaction evaluation was higher than that the combined treatment group(P<0.05).Conclusion Caproxin aminintriol injection and uterine filling in placenta previa after cesarean section.